EXTRACTION AND HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHIC DETERMINATION OF ENDOFLOXACIN IN FISH SERUM AND TISSUES

被引：17

作者：

ROGSTAD, A ^{[1
]}

HORMAZABAL, V ^{[1
]}

YNDESTAD, M ^{[1
]}

机构：

[1] NORWEGIAN COLL VET MED,DEPT FOOD HYG,N-0033 OSLO 1,NORWAY

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1991年 / 14卷 / 03期

关键词：

D O I：

10.1080/01483919108049267

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The extraction of enrofloxacin from fish serum and tissues using solid phase extraction columns has been studied. Good recoveries were obtained by using C2 columns for clean-up of serum and C18 columns for clean-up of tissue samples. The sample pretreatment procedures are selective and robust having a sensitivity of 1 ng/ml and 1 ng/g from serum and tissues, respectively, making them particularly useful for monitoring drug residue levels. The recoveries were 97-100% from serum and 96-99% from tissues. The method was tested on fish treated with enrofloxacin.

引用

页码：521 / 531

页数：11

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