ALTERNATIVE PATHWAY ACTIVATION OF COMPLEMENT BY A MURINE PARASITIC NEMATODE (NEMATOSPIROIDES-DUBIUS)

被引：16

作者：

PROWSE, SJ ^{[1
]}

EY, PL ^{[1
]}

JENKIN, CR ^{[1
]}

机构：

[1] UNIV ADELAIDE,DEPT MICROBIOL & IMMUNOL,ADELAIDE 5001,S AUSTRALIA,AUSTRALIA

来源：

AUSTRALIAN JOURNAL OF EXPERIMENTAL BIOLOGY AND MEDICAL SCIENCE | 1979年 / 57卷 / OCT期

关键词：

D O I：

10.1038/icb.1979.47

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

The cuticular surface of the infectious third-stage larvae of Nematospiroides dubius activates complement via the alternative pathway. Sensitisation of larvae with complement or with antibodies from the serum of immune mice (resistant to reinfection) promoted the adherence of mouse peritoneal exudate cells to the larval cuticle during incubation in vitro. The infectivity of larvae sensitised with antibody or complement was significantly reduced after incubation with cells from immune mice.

引用

页码：459 / 466

页数：8

共 18 条

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