EFFECT OF INDOMETHACIN, EPINEPHRINE, PROSTAGLANDIN E-2 AND INSULIN ON LIPOLYSIS IN BOVINE ADIPOSE-TISSUE INVITRO

被引：2
作者：
DIMARCO, NM
RULE, DC
WHITEHURST, GB
BEITZ, DC
机构：
[1] IOWA STATE UNIV SCI & TECHNOL,DEPT ANIM SCI,AMES,IA 50011
[2] TEXAS WOMANS UNIV,DEPT NUTR & FOOD SCI,DENTON,TX 76204
[3] UNIV WYOMING,DEPT ANIM SCI,LARAMIE,WY 82071
[4] ATLANTIC CHRISTIAN COLL,DEPT SCI,WILSON,NC 27893
来源：
INTERNATIONAL JOURNAL OF BIOCHEMISTRY | 1991年 / 23卷 / 11期
关键词：
D O I：
10.1016/0020-711X(91)90221-8
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
1. Fasting of ad libitum- or maintenance-fed steers for 4 to 9 days did not alter basal lipolytic rates in vitro. 2. Epinephrine stimulation of adipose tissue of fasted steers resulted in greater (P < 0.05) lipolysis than in tissue from fed steers. 3. Prostaglandin E2 (PGE2) did not alter epinephrine-stimulated lipolysis in ad libitum- or maintenance-fed cattle. 4. Indomethacin did not influence basal lipolysis, even in the presence of PGE2. 5. Insulin neither affected basal lipolysis nor inhibited dibutyl cAMP-stimulated lipolysis.
引用
收藏
页码：1231 / 1235
页数：5
相关论文
共 29 条
[1]  
ARNER P, 1976, ACTA MED SCAND, V200, P273
[2]   INFLUENCE OF NUTRITIONAL STATE ON INHIBITION OF LIPOLYSIS IN ADIPOSE TISSUE BY PROSTAGLANDIN E1 AND NICOTINIC ACID - PROSTAGLANDIN AND RELATED FACTORS 46 [J].
BERGSTROM, S ;
CARLSON, LA .
ACTA PHYSIOLOGICA SCANDINAVICA, 1965, 65 (04) :383-+
[3]  
CARLSON L A, 1970, Acta Physiologica Scandinavica, V80, P289, DOI 10.1111/j.1748-1716.1970.tb04792.x
[4]   BIOSYNTHESIS AND POSSIBLE FUNCTION OF PROSTAGLANDINS IN ADIPOSE TISSUE [J].
CHRIST, EJ ;
NUGTEREN, DH .
BIOCHIMICA ET BIOPHYSICA ACTA, 1970, 218 (02) :296-+
[5]   PROSTAGLANDIN INHIBITION OF CYCLIC-AMP ACCUMULATION AND RATE OF LIPOLYSIS IN FAT-CELLS [J].
DALTON, C ;
HOPE, H ;
MARTIKES, L .
PROSTAGLANDINS, 1974, 7 (04) :319-326
[6]   INABILITY OF PROSTAGLANDIN SYNTHESIS INHIBITORS TO AFFECT ADIPOSE-TISSUE LIPOLYSIS [J].
DALTON, C ;
HOPE, HR .
PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1973, 4 (05) :641-651
[7]   CYCLIC-AMP REGULATION OF PROSTAGLANDIN BIOSYNTHESIS IN FAT-CELLS [J].
DALTON, C ;
HOPE, WC .
PROSTAGLANDINS & OTHER LIPID MEDIATORS, 1974, 6 (03) :227-242
[8]   EVALUATION OF PROSTAGLANDIN-E2 AS A REGULATOR OF LIPOLYSIS IN BOVINE ADIPOSE-TISSUE [J].
DIMARCO, NM ;
WHITEHURST, GB ;
BEITZ, DC .
JOURNAL OF ANIMAL SCIENCE, 1986, 62 (02) :363-369
[9]   INDOMETHACIN, LIPOLYSIS AND CYCLIC-AMP ACCUMULATION IN WHITE FAT-CELLS [J].
FAIN, JN ;
PSYCHOYOS, S ;
CZERNIK, AJ ;
FROST, S ;
CASH, WD .
ENDOCRINOLOGY, 1973, 93 (03) :632-639
[10]   INDOMETHACIN AND ROLE OF PROSTAGLANDINS IN ADIPOSE-TISSUE [J].
FREDHOLM, BB ;
HEDQVIST, P .
BIOCHEMICAL PHARMACOLOGY, 1975, 24 (01) :61-66
123