Chronic hepatitis C: This and the new era of treatment

被引:60
作者
Bertino, Gaetano [1 ]
Ardiri, Annalisa [1 ]
Proiti, Maria [1 ]
Rigano, Giuseppe [1 ]
Frazzetto, Evelise [1 ]
Demma, Shirin [1 ]
Ruggeri, Maria Irene [2 ]
Scuderi, Laura [1 ]
Malaguarnera, Giulia [3 ,4 ]
Bertino, Nicoletta [5 ]
Rapisarda, Venerando [6 ]
Di Carlo, Isidoro [7 ]
Toro, Adriana [7 ]
Salomone, Federico [8 ]
Malaguarnera, Mariano [3 ]
Bertino, Emanuele [5 ]
Malaguarnera, Michele [3 ,4 ]
机构
[1] Univ Catania, Dept Clin & Expt Med, Hepatol Unit, I-95123 Catania, Italy
[2] ARNAS Civ Hosp, Internal Med Unit, I-90142 Palermo, Italy
[3] Univ Catania, Res Ctr La Grande Senesce, I-95100 Catania, Italy
[4] Univ Catania, Dept Biomed Sci, I-95100 Catania, Italy
[5] Univ Catania, Fac Pharm, I-95123 Catania, Italy
[6] Univ Catania, Dept Clin & Expt Med, Occupat Med Unit, I-95100 Catania, Italy
[7] Univ Catania, Dept Surg Sci Organ Transplantat & Adv Technol, I-95100 Catania, Italy
[8] Acireale Hosp, Gastroenterol Unit, I-95024 Catania, Italy
关键词
Direct-acting antiviral agents; Nucleoside inhibitors; Boceprevir; Sofosbuvir; Telaprevir; Hepatitis C; Simeprevir; Daclatasvir; Ledipasvir; Faldaprevir; Ritonavir; Ombitasvir; Dasabuvir;
D O I
10.4254/wjh.v8.i2.92
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
Over the last years it has started a real revolution in the treatment of chronic hepatitis C. This occurred for the availability of direct-acting antiviral agents that allow to reach sustained virologic response in approximately 90% of cases. In the near future further progress will be achieved with the use of pan-genotypic drugs with high efficacy but without side effects.
引用
收藏
页码:92 / 106
页数:15
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