RESCUE OF VACCINIA VIRUS LACKING THE E3L GENE BY MUTANTS OF E3L

被引：107

作者：

CHANG, HW

URIBE, LH

JACOBS, BL

机构：

[1] ARIZONA STATE UNIV,DEPT MICROBIOL & MOLEC & CELLULAR BIOL,GRAD DEGREE PROGRAM,TEMPE,AZ 85287

[2] UNIV COSTA RICA RODRIGO FACIO,FAC MICROBIOL,VIROL LAB,SAN JOSE,COSTA RICA

来源：

JOURNAL OF VIROLOGY | 1995年 / 69卷 / 10期

关键词：

D O I：

10.1128/JVI.69.10.6605-6608.1995

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Vaccinia virus with the E3L gene deleted was able to replicate in RK-13 but not HeLa cells. This host range phenotype could be complemented by an E3L gene expressed transiently from a plasmid. Analysis of mutants of E3L indicates that the ability to complement deletion of E3L correlates with the ability of mutated proteins to bind double-stranded RNA bat not with their ability to migrate to the nucleus.

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页码：6605 / 6608

页数：4

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