PROPERTIES AND MECHANISMS OF LONG-TERM SYNAPTIC PLASTICITY IN THE MAMMALIAN BRAIN - RELATIONSHIPS TO LEARNING AND MEMORY

被引：182

作者：

MAREN, S ^{[1
]}

BAUDRY, M ^{[1
]}

机构：

[1] UNIV SO CALIF, NEUROSCI PROGRAM, LOS ANGELES, CA 90089 USA

来源：

NEUROBIOLOGY OF LEARNING AND MEMORY | 1995年 / 63卷 / 01期

关键词：

D O I：

10.1006/nlme.1995.1001

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Long-term potentiation (LTP) in the hippocampus and long-term depression (LTD) in the cerebellum are two forms of long-lasting synaptic plasticity that currently serve as our primary experimental models of learning and memory formation in mammals. In recent years, there have been considerable advances in our understanding of the cellular and molecular mechanisms of these and other forms of synaptic plasticity. This article presents an overview of these developments, considers the relationship of long-term synaptic plasticity mechanisms to learning and memory in view of these developments, and suggests future directions for research in this rapidly growing area of neuroscience. (C) 1995 Academic Press, Inc.

引用

页码：1 / 18

页数：18

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