Clinical Evaluations of 49 Cases with Kawasaki Disease: A Retrospective Cohort Study

Objective: Kawasaki disease is the most common cause of an acute febrile vasculitis with unknown etiology after Henoch-Schnlein purpura ( HSP). The aim of our study is to contribute data on Kawasaki disease, which may lead to severe cardiac complications and death when it is misdiagnosed or not treated appropriately. Material and Methods: The demographic and clinical characteristics and laboratory and treatment outcomes of patients with Kawasaki disease who were diagnosed between January 2005 and December 2010 were evaluated respectively. Results: Out of 49 patients, 17 of 49 (34.7%) were female and 32 of 49 (65.3%) were male. The female/male ratio was 1.88. The average age of patients was 2.89 +/- 1.95 years. It was detected that the frequency of Kawasaki disease was increased in autumn and early winter, and the second peak was detected in June. Thirty-four of 49 (69%) patients had complete Kawasaki disease and 15 of 49 ( 31%) patients had incomplete disease. Changes in oral cavity concomitant fewer were the most frequent clinical findings ( 79.6%). Coronary artery abnormalities were detected in 13 of 49 patients (26.5%). Any significant correlation was found between abnormal echocardiography outcomes, and risk factors average age, duration of fewer, anemia, thrombocytosis, elevated erythrocyte sedimentation rate, positive C-reactive protein, elevated serum transaminases, hyponatremia, and hypoalbuminemia. Conclusion: The cardiovascular complications in patients with Kawasaki disease are the reason that morbidity and mortality might be prevented by early diagnosis and treatment.