Application of Microfluidic Technique in Drug Delivery

被引：3

作者：

Guan, Wenjian ^{[1
]}

Zhang, Yi ^{[2
]}

机构：

[1] Auburn Univ, Dept Chem Engn, 212 Ross Hall, Auburn, AL 36849 USA

[2] Georgia Inst Technol, Sch Chem & Biomol Engn, Atlanta, GA 30332 USA

来源：

NANO LIFE | 2016年 / 6卷 / 3-4期

基金：

美国国家科学基金会;

关键词：

Drug delivery; microfluidic; microparticles; biomaterials;

D O I：

10.1142/S1793984416420095

中图分类号：

TB3 [工程材料学]; R318.08 [生物材料学];

学科分类号：

0805 ; 080501 ; 080502 ;

摘要：

Drug delivery as a strategy to improve the effect therapeutic treatment is gaining tremendous interest in biomedical research. The recent advancement in microfluidic technique designed to precisely control the liquid at micro or nano liter level has shed some new lights on reshaping the ongoing drug delivery research. In this aspect, this present mini-review gives an overview on the potential applications of microfluidic technique in the area of drug delivery, which basically covers the fabrication of drug delivery carriers and the design of microfluidic-based smart systems for localized in vivo drug delivery.

引用

页数：10

共 51 条

[1] RECENT ADVANCES ON THE USE OF BIODEGRADABLE MICROPARTICLES AND NANOPARTICLES IN CONTROLLED DRUG-DELIVERY [J].

BRANNONPEPPAS, L .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 1995, 116 (01) :1-9

[2] Design, production and optimization of solid lipid microparticles (SLM) by a coaxial microfluidic device [J].

Capretto, Lorenzo ;

Mazzitelli, Stefania ;

Nastruzzi, Claudio .

JOURNAL OF CONTROLLED RELEASE, 2012, 160 (03) :409-417

[3] Liposome production by microfluidics: potential and limiting factors [J].

Carugo, Dario ;

Bottaro, Elisabetta ;

Owen, Joshua ;

Stride, Eleanor ;

Nastruzzi, Claudio .

SCIENTIFIC REPORTS, 2016, 6

[4] Designer Polymer-Based Microcapsules Made Using Microfluidics [J].

Chen, Philipp W. ;

Erb, Randall M. ;

Studart, Andre R. .

LANGMUIR, 2012, 28 (01) :144-152

[5] A robust, electrochemically driven microwell drug delivery system for controlled vasopressin release [J].

Chung, Aram J. ;

Huh, Yun Suk ;

Erickson, David .

BIOMEDICAL MICRODEVICES, 2009, 11 (04) :861-867

[6] Droplet-based microfluidic platforms for the encapsulation and screening of mammalian cells and multicellular organisms (vol 15, pg 427, 2008) [J].

Clausell-Tormos, Jenifer ;

Lieber, Diana ;

Baret, Jean-Christophe ;

El-Harrak, Abdeslam ;

Miller, Oliver J. ;

Frenz, Lucas ;

Blouwolff, Joshua ;

Humphry, Katherine J. ;

Koester, Sarah ;

Duan, Honey ;

Holtze, Christian ;

Weitz, David A. ;

Griffiths, Andrew D. ;

Merten, Christoph A. .

CHEMISTRY & BIOLOGY, 2008, 15 (08) :875-875

[7] MEMS: Enabled Drug Delivery Systems [J].

Cobo, Angelica ;

Sheybani, Roya ;

Meng, Ellis .

ADVANCED HEALTHCARE MATERIALS, 2015, 4 (07) :969-982

[8] Microfluidic synthesis of advanced microparticles for encapsulation and controlled release [J].

Duncanson, Wynter J. ;

Lin, Tina ;

Abate, Adam R. ;

Seiffert, Sebastian ;

Shah, Rhutesh K. ;

Weitz, David A. .

LAB ON A CHIP, 2012, 12 (12) :2135-2145

[9] Microfluidic based high throughput synthesis of lipid-polymer hybrid nanoparticles with tunable diameters [J].

Feng, Qiang ;

Zhang, Lu ;

Liu, Chao ;

Li, Xuanyu ;

Hu, Guoqing ;

Sun, Jiashu ;

Jiang, Xingyu .

Biomicrofluidics, 2015, 9 (05)

[10] The mechanisms of drug release in poly(lactic-co-glycolic acid)-based drug delivery systems-A review [J].

Fredenberg, Susanne ;

Wahlgren, Marie ;

Reslow, Mats ;

Axelsson, Anders .

INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2011, 415 (1-2) :34-52

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