ANALYSIS OF 309 CASES OF ESOPHAGEAL ATRESIA FOR ASSOCIATED CONGENITAL-MALFORMATIONS

被引：26

作者：

ROKITANSKY, A

KOLANKAYA, A

BICHLER, B

MAYR, J

MENARDI, G

机构：

[1] Pediatric Surgery Clinics of University of Vienna (A.R., A.K.), Vienna

[2] Landeskrankenhaus Linz (B.B.), Linz

[3] University of Graz (J.M.), Graz

[4] University of Innsbruck (G.M.), Innsbruck

来源：

AMERICAN JOURNAL OF PERINATOLOGY | 1994年 / 11卷 / 02期

关键词：

D O I：

10.1055/s-2007-994571

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Three hundred nine cases of esophageal atresia were retrospectively investigated. One hundred and sixty-two (52.4%) had associated congenital malformations. The total number of malformations was 357. The eight groups of malformations in decreasing order of frequency were as follows: cardiac, 72 cases (23.3%); musculoskeletal, 55 cases (17.8%); anointestinal, 50 cases (16.2%); genitourinary, 45 cases (14.6%); head and neck, 31 cases (10.0%); mediastinal, 26 cases (8.4%); chromosomal, 17 cases (5.5%); pulmonary, 6 cases (1.9%). Of the 162 cases with associated malformations, 83 (51.2%) had a single group of malformations, 41 (25.3%) had two groups of malformations, and 38 (23.5%) had three or more groups of malformations. More than 50% of pulmonary (83.3%), head and neck (77.4%), chromosomal (58.8%), and mediastinal malformations (53.8%) were found in association with cardiac malformations. The frequency of associated malformations in esophageal atresia cases was found to be, increased significantly during the investigated interval. Early gestational age and lower birthweights were significantly correlated with higher rates of malformations. The survival rate of patients with esophageal atresia was also found to be significantly increasing over time. The mean survival rates over 32 years for groups with and without malformations were 38.3% and 70.7%, respectively, and were statistically significant. The mean survival rates of the same groups in the last 5 years were found to have changed dramatically, rising to 62.9 in the group with malformations and to 100% in the group without malformations; again, the difference is significant.

引用

页码：123 / 128

页数：6

共 13 条

[1] Bishop P.J., Klein M.D., Philippart A.I., Et al., TranspIeural repair of esophageal airesia without a primary gastrostomy: 240 patients treated between 1951 and 1983, J Pediatr Surg, 20, (1985)
[2] Connollv B., Guinev E.J., Trends in tracheoesophageal fistula, Surg Gynecol Óbstet, 164, (1987)
[3] Louhimo 1, Lindahl 11. Esophageal atresia: Primary results of 500 consecutively treated patients, J Pediatr Surg, 18, (1983)
[4] Rokitansky A.M., Kolankaya A.A.V., Seidl S., Et al., Recent evaluation of prognostic risk factors in esophageal atresia—a multicenter review of 223 cases, Eur J Pediatr Surg, 3, pp. 196-201, (1992)
[5] Waterston D.J., Bonham-Carter R.E., Aberdeen E., Oesophageal atresia, tracheoesophageal fistula—a study of survival in 218 infants, Lancet, 1, (1962)
[6] Chittmittrapap S., Spitz L., Kiely E.M., Et al., Anastomotic stricture following repair of esophageal atresia, J Pediatr Surg, 25, (1990)
[7] Kagelman K.M., Boyarsky A., Temporary banding of the gas-troesophageal junction in the critically ill neonate with esophageal atresia and tracheoesophageal fistula, Surgery, 98, (1985)
[8] Malmfors G., Okmian L., End-to-end anastomosis in esopha-geal atresia—clinical application of experimental experiences, Z Kinderchir, 40, pp. 67-70, (1985)
[9] Myers N.A., Beasley S.W., Auldisl A.W., Oesophageal atresia and associated anomalies: A plea for uniform documentation, Pediatr Surg Int, 7, pp. 97-100, (1992)
[10] Ein S.H., Shandling B., Wesson D.E., Et al., Esophageal atresia with distal tracheoesophageal fistula: Associated anomalies and prognosis in the 1980s, J Pediatr Surg, 24, (1989)

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