LEAD-TETRAACETATE CLEAVAGE OF CHIRAL PHENYLGLYCINOL DERIVED SECONDARY-AMINES WITHOUT RACEMIZATION

被引：30

作者：

MOKHALLALATI, MK ^{[1
]}

PRIDGEN, LN ^{[1
]}

机构：

[1] SMITHKLINE BEECHAM PHARMACEUT,DEPT SYNTHET CHEM,POB 1539,KING OF PRUSSIA,PA 19406

来源：

SYNTHETIC COMMUNICATIONS | 1993年 / 23卷 / 14期

关键词：

D O I：

10.1080/00397919308009866

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Diastereomerically enriched N-(1,1-disubstituted methyl)(2-hydroxy-1'-phenylethyl)amines were oxidatively converted to enantiomerically enriched primary disubstituted methylamines in excellent yields without racemization, using an improved lead tetraacetate (LTA) procedure.

引用

页码：2055 / 2064

页数：10

共 18 条

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