METABOLIC MAPPING OF FUNCTIONAL-ACTIVITY IN THE HYPOTHALAMO-NEUROHYPOPHYSEAL SYSTEM OF THE RAT

被引：413

作者：

SCHWARTZ, WJ

SMITH, CB

DAVIDSEN, L

SAVAKI, H

SOKOLOFF, L

MATA, M

FINK, DJ

GAINER, H

机构：

[1] NICHHD,BEHAV BIOL BRANCH,BETHESDA,MD 20014

[2] NICHHD,FUNCT NEUROCHEM SECT,BETHESDA,MD 20014

来源：

SCIENCE | 1979年 / 205卷 / 4407期

关键词：

D O I：

10.1126/science.462184

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Physiological stimulation of the hypothalamo-neurohypophysial system by salt loading of rats resulted in a dramatically increased glucose utilization in the posterior pituitary but not in the paraventricular or supraoptic nuclei. The good correlation between glucose utilization and neural activity in the posterior pituitary (that is, nerve terminals) contrasted with the lack of correlation in the paraventricular and supraoptic nuclei (that is, the sites of the cell bodies of the same neurons). This difference in the metabolic response to functional activity between the two regions of these neurons can be explained by the differences in surface-to-volume ratios of these regions.

引用

页码：723 / 725

页数：3

共 26 条

[1] EFFECT OF AUTONOMIC BLOCKING AGENTS ON VASOPRESSIN RELEASE IN-VIVO INDUCED BY OSMORECEPTOR STIMULATION [J].