Clinical characteristics of Fuchs' Heterochromic Iridocyclitis in a tertiary medical center in Makkah region of Saudi Arabia: A retrospective study

Objectives: To characterize the clinical features of Fuchs' Heterochromic Iridocyclitis in a Saudi population. Methods: Retrospective analysis of the records of the consecutive patients presented to the uveitis clinic, Magrabi Eye and Ear Hospital, Jeddah, Saudi Arabia, between 2001and 2011. Results: We enrolled 21 eyes of 19 patients with the diagnosis of Fuch's Heterochromic lridocyclitis who completed a minimum of 6 months follow up. The mean follow up was 25 +/- 13.35 (range 6 48) months. Males predominated (13/19, 68.3%). Majority (17/19. 89.5%) had unilateral presentation. The age at presentation was 36.2 +/- 11 (range 18-59) years. 31.6% (6/19) showed heterochromia. All patients (100%) showed fine stellate filamentary keratic precipitates and majority (57.9 degrees,0 showed mild ( < 1/2 cells and < 1/2 flare) anterior chamber inflammation. Iris atrophy was seen in majority (15/19, 78.9%) of patients. All (100%) showed fine vitreous cells and vitreous debris. In majority of patients (15/19, 78.9%) Iris nodules were absent. Koeppe nodules were seen in 15.8% (3/19) patients. Peripheral anterior synechiae was noted in 3 (15.8%) patients and 2 of them had elevated intraocular pressure which responded to anti glaucoma treatment. All patients had developed cataracts. Best corrected visual acuity was better than 0.5 in 12/19 (63.2%) of patients at the final follow up. Conclusion: Our patients had less heterochromia and Iris nodules. Subtle iris atrophy with fine keratic precipitates and very mild anterior chamber inflammation (< 1/2 cells, < 1/2 flare) along with tine vitreous cells and debris could lead to the diagnosis of Fuch's I leterochromic Iridocyclitis in our population.