The absolute configuration of an intermediate cyclic sulfoximine in the asymmetric synthesis of transition-state analog inhibitors of gamma-glutamylcysteine synthetase

被引：1

作者：

Tokutake, N ^{[1
]}

Hiratake, J

Irie, T

Yamano, A

Oda, J

机构：

[1] Kyoto Univ, Inst Chem Res, Kyoto 6110011, Japan

[2] Rigaku Corp, Tokyo 1968666, Japan

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS | 1999年 / 55卷

关键词：

D O I：

10.1107/S0108270198016436

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The crystal structure of a cyclic sulfoximine, 2-amino-4-(4-ethyl-1,3-dioxo-4,5-dihydra-1,2-thiazol-1-yl)butanoic acid, C9H16N2O4S, was determined to ascertain its stereochemistry. The absolute configuration of the chiral S atom was S on the basis of the (S)-alpha-carbon derived from the synthetic precursor, L-homocysteine.

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页码：1598 / 1599

页数：2

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