Microwaves for breast cancer treatments

被引:13
作者
Elkayal, Heba Abdelhamid [1 ]
Ismail, Nour Eldin [2 ]
Lotfy, Mona [2 ]
机构
[1] PUA, Fac Engn, Dept Elect, Alexandria, Egypt
[2] Univ Alexandria, Fac Engn, Dept Elect, Alexandria, Egypt
关键词
Hyperthermia; APA; COMSOL MULTIPHYSICS;
D O I
10.1016/j.aej.2015.06.012
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
Hyperthermia is potentially an effective method for the treatment of cancer, especially breast cancer tumors. One of the most attractive attributes of hyperthermia is the possibility of providing therapeutic benefit noninvasively, minimizing side effects. To be effective, a hyperthermia treatment must selectively heat the cancerous tissue, elevating the temperature in the tumor without exposing healthy tissue to excessive temperature elevations. In this paper, a suggested simple model of Annular Phased Array (APA) using eight half wavelength linear dipoles is presented. New software (COMSOL MULTIPHYSICS) is used to calculate the temperature distribution inside a model of a three layered breast (skin, breast tissue, and tumor). In addition, the effect of changing the amplitude and phases of the array elements on the temperature distributions and the conditions on the values of the phases are demonstrated in order to achieve the objective of hyperthermia for breast tumor treatment. (C) 2015 Faculty of Engineering, Alexandria University. Production and hosting by Elsevier B.V.
引用
收藏
页码:1105 / 1113
页数:9
相关论文
共 21 条
[1]   SAR OPTIMIZATION IN A PHASED-ARRAY RADIOFREQUENCY HYPERTHERMIA SYSTEM [J].
BARDATI, F ;
BORRANI, A ;
GERARDINO, A ;
LOVISOLO, GA .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1995, 42 (12) :1201-1207
[2]  
Berenger J-P, 1996, IEEE T ANTENNAS PROP, V44, P117
[3]   ANALYSIS AND OPTIMIZATION OF WAVE-GUIDE MULTIAPPLICATOR HYPERTHERMIA SYSTEMS [J].
BOAG, A ;
LEVIATAN, Y ;
BOAG, A .
IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING, 1993, 40 (09) :946-952
[4]   Ultrawide-band microwave space-time beamforming for hyperthermia treatment of breast cancer: A computational feasibility study [J].
Converse, M ;
Bond, EJ ;
Hagness, SC ;
Van Veen, BD .
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, 2004, 52 (08) :1876-1889
[5]   A computational study of ultra-wideband versus narrowband microwave hyperthermia for breast cancer treatment [J].
Converse, M ;
Bond, EJ ;
Van Veen, BD ;
Hagness, SC .
IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES, 2006, 54 (05) :2169-2180
[6]  
ENGQUIST B, 1977, MATH COMPUT, V31, P629, DOI 10.1090/S0025-5718-1977-0436612-4
[7]   Specific heat capacities of human and animal tissues [J].
Giering, K ;
Lamprecht, I ;
Minet, O .
LASER-TISSUE INTERACTION AND TISSUE OPTICS, PROCEEDINGS OF, 1996, 2624 :188-197
[8]  
Hansen R. C., 2009, PHASED ARRAY ANTENNA
[9]  
HIGDON RL, 1987, MATH COMPUT, V49, P65, DOI 10.1090/S0025-5718-1987-0890254-1
[10]   The cellular and molecular basis of hyperthermia [J].
Hildebrandt, B ;
Wust, P ;
Ahlers, O ;
Dieing, A ;
Sreenivasa, G ;
Kerner, T ;
Felix, R ;
Riess, H .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2002, 43 (01) :33-56