INTERACTION OF PORPHYROMONAS-GINGIVALIS WITH GINGIVAL EPITHELIAL-CELLS MAINTAINED IN CULTURE

被引：84
作者：
LAMONT, RJ
ODA, D
PERSSON, RE
PERSSON, GR
机构：
[1] Departments of Oral Biology, School of Dentistry, University of Washington, Seattle
[2] Departments of Periodontics, School of Dentistry, University of Washington, Seattle
来源：
ORAL MICROBIOLOGY AND IMMUNOLOGY | 1992年 / 7卷 / 06期
关键词：
PORPHYROMONAS-GINGIVALIS; EPITHELIAL CELL; INVASION;
D O I：
10.1111/j.1399-302X.1992.tb00637.x
中图分类号：
R78 [口腔科学];
学科分类号：
1003 ;
摘要：
Interactions between Porphyromonas gingivalis and gingival epithelial cells were investigated. Gingival epithelial cells were cultured from surgically removed gingival tissue. Electron microscopy demonstrated adherence of P. gingivalis to the cell membranes and microvilli followed by internalization of the bacteria into the epithelial cell cytoplasm. Saliva from healthy and periodontally diseased patients inhibited P gingivalis association with the epithelial cells. Attachment to and penetration of gingival epithelial cells by P. gingivalis may be important virulence factors in periodontal disease. Salivary molecules may play a role in modulating these interactions.
引用
收藏
页码：364 / 367
页数：4
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