Neurologic manifestations of intravascular large B-cell lymphoma

被引：22

作者：

Tahsili-Fahadan, Pouya ^{[1
,2
]}

Rashidi, Armin ^{[6
]}

Cimino, Patrick J. ^{[7
]}

Bucelli, Robert C. ^{[1
,2
,3
]}

Keyrouz, Salah G. ^{[1
,4
,5
]}

机构：

[1] Washington Univ, Sch Med, Dept Neurol, St Louis, MO 63110 USA

[2] Washington Univ, Sch Med, Div Gen Neurol, St Louis, MO USA

[3] Washington Univ, Sch Med, Div Neuromuscular Disorders, St Louis, MO USA

[4] Washington Univ, Sch Med, Div Cerebrovasc Dis, St Louis, MO 63130 USA

[5] Washington Univ, Sch Med, Div Neurol Crit Care, St Louis, MO 63130 USA

[6] Washington Univ, Sch Med, Div Oncol, St Louis, MO USA

[7] Washington Univ, Sch Med, Dept Pathol & Immunol, Div Neuropathol, St Louis, MO USA

来源：

NEUROLOGY-CLINICAL PRACTICE | 2016年 / 6卷 / 01期

关键词：

D O I：

10.1212/CPJ.0000000000000185

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Purpose of review: Intravascular large B-cell lymphoma is a rare subtype of large B-cell lymphoma that affects various organs including the nervous system. The diagnosis is challenging and frequently made at autopsy. Recent findings: We report 5 cases with an array of neurologic manifestations. All patients were initially evaluated for alternative diagnoses. Three patients were diagnosed at autopsy, one with brain biopsy, and another with muscle biopsy. Muscle was involved in all 3 patients who had muscle tissue available for analysis. Summary: Our observations suggest that random open muscle biopsy may present a high-yield, less invasive option for the diagnosis of this disorder.

引用

页码：55 / 60

页数：6

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