Novel and Efficient Microwave-Assisted Three Component Reaction for the Synthesis of Oxazine Derivatives

Oxazine derivatives can be prepared with yield upto 98% within a few minutes by an efficient and novel one pot microwave- assisted three- component reaction from 1-naphthol, various anilines and formalin using montmorillonite as the catalyst. The procedure is very simple, efficient and environmentally friendly as it does not use any toxic auxiliary or solvent. The key advantages of this process are high yields, shorter reaction times, and easy work-up and non - chromatographic method has been used for the purification of products.