SENSITIZATION IN APLYSIA - RESTORATION OF TRANSMISSION IN SYNAPSES INACTIVATED BY LONG-TERM HABITUATION

被引：48

作者：

CAREW, T ^{[1
]}

CASTELLUCCI, VF ^{[1
]}

KANDEL, ER ^{[1
]}

机构：

[1] COLUMBIA UNIV COLL PHYS & SURG, DEPT PSYCHIAT, DIV BEHAV, NEW YORK, NY 10032 USA

来源：

SCIENCE | 1979年 / 205卷 / 4404期

关键词：

D O I：

10.1126/science.451611

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Long-term habituation of a simple withdrawal reflex in Aplysia leads to an inactivation of synaptic transmission between identified sensory and gill motor neurons that persists for more than 3 weeks. A single sensitizing stimulus rapidly reactivates both the depressed behavioral response and the inactivated synaptic transmission. Thus sensitization, a simple competitive form of learning, provides a mechanism whereby changing environmental demands can rapidly override the long-term memory of habituation. Copyright © 1979 AAAS.

引用

页码：417 / 419

页数：3

共 9 条

[1]

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