EFFECTS OF THERAPY WITH BENDROFLUMETHIAZIDE IN PATIENTS WITH RECURRENT RENAL CALCIUM STONES

被引：59

作者：

BACKMAN, U ^{[1
]}

DANIELSON, BG ^{[1
]}

JOHANSSON, G ^{[1
]}

LJUNGHALL, S ^{[1
]}

WIKSTROM, B ^{[1
]}

机构：

[1] UNIV UPPSALA HOSP,DEPT INTERNAL MED,DIV NEPHROL,S-75014 UPPSALA,SWEDEN

来源：

BRITISH JOURNAL OF UROLOGY | 1979年 / 51卷 / 03期

关键词：

D O I：

10.1111/j.1464-410X.1979.tb02860.x

中图分类号：

R5 [内科学]; R69 [泌尿科学（泌尿生殖系疾病）];

学科分类号：

1002 ; 100201 ;

摘要：

Summary— Forty‐four patients with recurrent formation of calcium‐containing renal stones were treated with bendroflumethiazide for at least 2 years. Prior to treatment each patient had formed, on average, one stone per year for 8 years; during treatment only 4 patients formed new stones. A reduction in urinary calcium excretion was seen in almost all patients irrespective of their initial urinary calcium level. The apparent clinical benefit was not related to pre‐treatment urinary electrolyte levels. Side effects were slight: one patient developed symptomatic hyperuricaemia and in one case sustained hypercalcaemia was found. Long‐term treatment with thiazides appears to be a safe and effective method for the prevention of recurrent calcium stones. Copyright © 1979, Wiley Blackwell. All rights reserved

引用

页码：175 / 180

页数：6

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