ANTIINFLUENZA VIRUS ACTIVITY OF SYNTHETICALLY POLYMERIZED PHENYLPROPENOIDS

被引：25
作者：
SAKAGAMI, H
NAGATA, K
ISHIHAMA, A
OHHARA, T
KAWAZOE, Y
机构：
[1] NATL INST GENET, DEPT MOLEC GENET, MISHIMA, SHIZUOKA 411, JAPAN
[2] NAGOYA CITY UNIV, FAC PHARMACEUT SCI, DEPT PHARMACEUT CHEM, MIZUHO KU, NAGOYA, AICHI 467, JAPAN
来源：
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS | 1990年 / 172卷 / 03期
关键词：
D O I：
10.1016/0006-291X(90)91586-H
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Various dehydrogenation polymers (the so-called synthetic lignins) were synthesized from four different phenylpropenoids by endwise and bulk polymerizations and investigated for their anti-influenza virus activity. All of these materials suppressed the plaque formation of influenza virus infecting MDCK cells and the RNA-dependent RNA synthesis as effectively as the high molecular weight lignin-related extract (Fr. VI) of pine cone of Pinus parviflora Sieb. et Zucc. The structural simplicity and higher solubility of the synthesized polymers suggest that they might be regarded as potential candidates for medicinal antiviral resources. © 1990.
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页码：1267 / 1272
页数：6
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