PRELIMINARY STUDIES OF THE MODE OF ACTION OF ARILDONE, A NOVEL ANTI-VIRAL AGENT

被引：20

作者：

KUHRT, MF

FANCHER, MJ

JASTY, V

PANCIC, F

CAME, PE

机构：

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 1979年 / 15卷 / 06期

关键词：

D O I：

10.1128/AAC.15.6.813

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Arildone (also known as Win 38020), a novel aryl diketone, inhibited replication of herpes simplex virus type 2 in tissue culture by interfering with an event that occurs prior to 6 h postinfection. The inhibition could be paritally reversed by washing. Although the exact mechanism of action is unknown, neither viral deoxyribonucleic acid nor viral proteins were synthesized in the presence of arildone.

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页码：813 / 819

页数：7

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