EFFECTS OF ML-236B (COMPACTIN) ON STEROL SYNTHESIS AND LOW-DENSITY LIPOPROTEIN RECEPTOR ACTIVITIES IN FIBROBLASTS OF PATIENTS WITH HOMOZYGOUS FAMILIAL HYPERCHOLESTEROLEMIA

被引：25

作者：

HABA, T ^{[1
]}

MABUCHI, H ^{[1
]}

YOSHIMURA, A ^{[1
]}

WATANABE, A ^{[1
]}

WAKASUGI, T ^{[1
]}

TATAMI, R ^{[1
]}

UEDA, K ^{[1
]}

UEDA, R ^{[1
]}

KAMETANI, T ^{[1
]}

KOIZUMI, J ^{[1
]}

MIYAMOTO, S ^{[1
]}

TAKEDA, R ^{[1
]}

TAKESHITA, H ^{[1
]}

机构：

[1] FUKUI PREFECTURAL HOSP,FUKUI 910,JAPAN

来源：

JOURNAL OF CLINICAL INVESTIGATION | 1981年 / 67卷 / 05期

关键词：

D O I：

10.1172/JCI110184

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

引用

页码：1532 / 1540

页数：9

共 29 条

[1] Brown M S, 1975, Adv Intern Med, V20, P273
[2] BROWN MS, 1974, J BIOL CHEM, V249, P789
[3] BROWN MS, 1978, J BIOL CHEM, V253, P1121
[4] COMPETITIVE INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE BY ML-236A AND ML-236B FUNGAL METABOLITES, HAVING HYPOCHOLESTEROLEMIC ACTIVITY
ENDO, A
KURODA, M
TANZAWA, K
[J]. FEBS LETTERS, 1976, 72 (02) : 323 - 326
[5] INHIBITION OF CHOLESTEROL-SYNTHESIS INVITRO AND INVIVO BY ML-236A AND ML-236B, COMPETITIVE INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL-COENZYME-A REDUCTASE
ENDO, A
TSUJITA, Y
KURODA, M
TANZAWA, K
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1977, 77 (01): : 31 - 36
[6] Fredrickson D. S., 1978, METABOLIC BASIS INHE, P604
[7] GENETIC-HETEROGENEITY IN FAMILIAL HYPERCHOLESTEROLEMIA - EVIDENCE FOR 2 DIFFERENT MUTATIONS AFFECTING FUNCTIONS OF LOW-DENSITY LIPOPROTEIN RECEPTOR
GOLDSTEIN, JL
DANA, SE
BRUNSCHEDE, GY
BROWN, MS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1975, 72 (03) : 1092 - 1096
[8] FAMILIAL HYPERCHOLESTEROLEMIA - IDENTIFICATION OF A DEFECT IN REGULATION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE-ACTIVITY ASSOCIATED WITH OVERPRODUCTION OF CHOLESTEROL
GOLDSTEIN, JL
BROWN, MS
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (10) : 2804 - 2808
[9] GENETICS OF LDL RECEPTOR - EVIDENCE THAT MUTATIONS AFFECTING BINDING AND INTERNALIZATION ARE ALLELIC
GOLDSTEIN, JL
BROWN, MS
STONE, NJ
[J]. CELL, 1977, 12 (03) : 629 - 641
[10] RELEASE OF LOW-DENSITY LIPOPROTEIN FROM ITS CELL-SURFACE RECEPTOR BY SULFATED GLYCOSAMINOGLYCANS
GOLDSTEIN, JL
BASU, SK
BRUNSCHEDE, GY
BROWN, MS
[J]. CELL, 1976, 7 (01) : 85 - 95

← 1 2 3 →