Application and Dosimetric Requirements for Gallium-68-labeled Somatostatin Analogues in Targeted Radionuclide Therapy for Gastroenteropancreatic Neuroendocrine Tumors

被引：13

作者：

Taieb, David ^{[1
,2
,3
]}

Garrigue, Philippe ^{[4
]}

Bardies, Manuel ^{[5
]}

Abdullah, Ahmad Esmaeel ^{[1
]}

Pacak, Karel ^{[6
]}

机构：

[1] Aix Marseille Univ, La Timone Univ Hosp, Dept Nucl Med, F-13385 Marseille, France

[2] Aix Marseille Univ, European Ctr Res Med Imaging, Marseille, France

[3] INSERM, Marseille Cancerol Res Ctr, Inst Paoli Calmettes, Marseille, France

[4] Aix Marseille Univ, La Timone Univ Hosp, Dept Radiopharm, Marseille, France

[5] UPS, INSERM, Canc Res Ctr Toulouse, UMR 1037, Toulouse, France

[6] Eunice Kennedy Shriver Natl Inst Child Hlth & Hum, Natl Inst Hlth, Program Reprod & Adult Endocrinol, Bethesda, MD 20892 USA

来源：

PET CLINICS | 2015年 / 10卷 / 04期

关键词：

PET; Gallium radioisotopes; Somatostatin; Gastroenteropancreatic; Neuroendocrine;

D O I：

10.1016/j.cpet.2015.06.001

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Theranostics of GEP-NETs based on 68Ga-labeled SSTa PET imaging and targeted therapy applying PRRT with 90Y-labeled and/or 177Lu-labeled SSTa has paved the way for personalized medicine ( Fig. 3). Future directions include the clinical use of somatostatin antagonists as targeting peptides for imaging and therapy47 and the development of novel receptor-targeting radiopharmaceuticals that hold promise for theranostics of NETs.

引用

页码：477 / 486

页数：10

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