What Is the Best Approach to Avoid Colorectal Cancer Risk in Inflammatory Bowel Disease?

被引：0

作者：

Baidoo, Leonard ^{[1
]}

Hanauer, Stephen B. ^{[2
]}

机构：

[1] Northwestern Univ, Feinberg Sch Med, Dept Gastroenterol & Hepatol, Ctr Inflammatory Bowel Dis, 676 N St Clair St,Suite 1400, Chicago, IL 60611 USA

[2] Northwestern Feinberg Sch Med, Digest Hlth Ctr, 676 N St Clair St,Suite 1400, Chicago, IL 60611 USA

来源：

CURRENT COLORECTAL CANCER REPORTS | 2016年 / 12卷 / 06期

关键词：

Inflammatory bowel disease; Ulcerative colitis; Crohn's disease; Duration of disease; Family history; Primary sclerosing cholangitis; Colorectal cancer; Risk factors; Surveillance; Colonoscopy; Dysplasia; Chromoendoscopy; Colectomy;

D O I：

10.1007/s11888-016-0339-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Inflammatory bowel diseases (IBD) comprise ulcerative colitis and Crohn's disease that primarily affect the colon and small intestine. IBD patients have a higher incidence of colorectal cancer (CRC) than the general population due to chronic colonic mucosal inflammation that predisposes to the development of dysplasia, the earliest form of neoplastic change in IBD and other chronic inflammatory disorders (e.g., Barrett's esophagus). Therefore, the two demonstrated means of reducing the risk of cancer in IBD are to control inflammation and to survey for dysplasia and remove the dysplastic area, if possible.

引用

页码：345 / 351

页数：7

共 61 条

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