A STEREOSELECTIVE SYNTHESIS OF CYCLOHEXYLNORSTATINE, THE KEY COMPONENT OF A RENIN INHIBITOR

被引:55
作者
MATSUMOTO, T
KOBAYASHI, Y
TAKEMOTO, Y
ITO, Y
KAMIJO, T
HARADA, H
TERASHIMA, S
机构
[1] SAGAMI CHEM RES CTR,SAGAMIHARA,KANAGAWA 229,JAPAN
[2] KISSEI PHARMACEUT CO LTD,CENT RES LABS,NAGANO 399,JAPAN
关键词
D O I
10.1016/S0040-4039(00)97574-9
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
The title synthesis could be accomplished by employing the novel addition reaction of a Grignard reagent with an imine in the presence of cerium(III) chloride. © 1990.
引用
收藏
页码:4175 / 4176
页数:2
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