POINT MUTATIONS IN CONSERVED AMINO-ACID RESIDUES WITHIN THE C-TERMINAL DOMAIN OF HIV-1 REVERSE-TRANSCRIPTASE SPECIFICALLY REPRESS RNASE-H FUNCTION

被引：157

作者：

SCHATZ, O ^{[1
]}

CROMME, FV ^{[1
]}

GRUNINGERLEITCH, F ^{[1
]}

LEGRICE, SFJ ^{[1
]}

机构：

[1] F HOFFMANN LA ROCHE & CO LTD, CENT RES UNIT, CH-4002 BASEL, SWITZERLAND

来源：

FEBS LETTERS | 1989年 / 257卷 / 02期

关键词：

D O I：

10.1016/0014-5793(89)81559-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：311 / 314

页数：4

共 22 条

[1]

BALTIMORE D, 1972, J BIOL CHEM, V247, P7282

[2] SUBREGIONS OF A CONSERVED PART OF THE HIV-GP41 TRANSMEMBRANE PROTEIN ARE DIFFERENTIALLY RECOGNIZED BY ANTIBODIES OF INFECTED INDIVIDUALS [J].

CERTA, U ;

BANNWARTH, W ;

STUBER, D ;

GENTZ, R ;

LANZER, M ;

LEGRICE, S ;

GUILLOT, F ;

WENDLER, I ;

HUNSMANN, G ;

BUJARD, H ;

MOUS, J .

EMBO JOURNAL, 1986, 5 (11) :3051-3056

[3] EMPIRICAL PREDICTIONS OF PROTEIN CONFORMATION [J].

CHOU, PY ;

FASMAN, GD .

ANNUAL REVIEW OF BIOCHEMISTRY, 1978, 47 :251-276

[4]

Crouch R. J., 1982, NUCLEASES, P211

[5] ANALYSIS OF ACCURACY AND IMPLICATIONS OF SIMPLE METHODS FOR PREDICTING SECONDARY STRUCTURE OF GLOBULAR PROTEINS [J].

GARNIER, J ;

OSGUTHORPE, DJ ;

ROBSON, B .

JOURNAL OF MOLECULAR BIOLOGY, 1978, 120 (01) :97-120

[6] SINGLE SUBUNIT FROM AVIAN MYELOBLASTOSIS VIRUS WITH BOTH RNA-DIRECTED DNA POLYMERASE AND RIBONUCLEASE-H ACTIVITY [J].

GRANDGENETT, DP ;

GERARD, GF ;

GREEN, M .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1973, 70 (01) :230-234

[7] IDENTIFICATION AND CHARACTERIZATION OF HIV-SPECIFIC RNASE-H BY MONOCLONAL-ANTIBODY [J].

HANSEN, J ;

SCHULZE, T ;

MELLERT, W ;

MOELLING, K .

EMBO JOURNAL, 1988, 7 (01) :239-243

[8] GENETIC APPROACH TO FACILITATE PURIFICATION OF RECOMBINANT PROTEINS WITH A NOVEL METAL CHELATE ADSORBENT [J].

HOCHULI, E ;

BANNWARTH, W ;

DOBELI, H ;

GENTZ, R ;

STUBER, D .

BIO-TECHNOLOGY, 1988, 6 (11) :1321-1325

[9] COMPUTER-ANALYSIS OF RETROVIRAL POL GENES - ASSIGNMENT OF ENZYMATIC FUNCTIONS TO SPECIFIC SEQUENCES AND HOMOLOGIES WITH NONVIRAL ENZYMES [J].

JOHNSON, MS ;

MCCLURE, MA ;

FENG, DF ;

GRAY, J ;

DOOLITTLE, RF .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (20) :7648-7652

[10] DEGRADATION OF DNA RNA HYBRIDS BY RIBONUCLEASE-H AND DNA POLYMERASES OF CELLULAR AND VIRAL ORIGIN [J].

KELLER, W ;

CROUCH, R .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (11) :3360-&

← 1 2 3 →