IMMUNOLOGICALLY IGNORANT AUTOREACTIVE T-CELLS, EPITOPE SPREADING AND REPERTOIRE LIMITATION

被引：127
作者：
ELSON, CJ
BARKER, RN
THOMPSON, SJ
WILLIAMS, NA
机构：
来源：
IMMUNOLOGY TODAY | 1995年 / 16卷 / 02期
基金：
英国惠康基金;
关键词：
D O I：
10.1016/0167-5699(95)80091-3
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
The factors that may cause antigen-presenting cells to alter the pattern of protein Processing and presentation to autoreactive T cells, and thereby stimulate autoimmune disease, are currently under debate. In this article, Chris Elson and colleagues suggest that cytokines associated with T helper 1 (Th1) cells alter the processing of proteins and that this effect can be counteracted by Th2-associated cytokines.
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页码：71 / 76
页数：6
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