SYNTHESIS OF COUMARINS AS SUBTYPE-SELECTIVE INHIBITORS OF MONOAMINE-OXIDASE

被引：41

作者：

RENDENBACHMULLER, B

SCHLECKER, R

TRAUT, M

WEIFENBACH, H

机构：

[1] KNOLL AG,DEPT CNS RES,D-67008 LUDWIGSHAFEN,GERMANY

[2] BASF AG,MAIN LAB,D-67056 LUDWIGSHAFEN,GERMANY

来源：

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS | 1994年 / 4卷 / 10期

关键词：

D O I：

10.1016/S0960-894X(01)80328-0

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

A series of coumarin derivatives was synthesized and evaluated as inhibitors of Monoamine Oxidase (MAO). Ether derivatives demonstrate MAO-B selectivity, sulfonic acid esters MAO-A selectivity.

引用

页码：1195 / 1198

页数：4