RESTRICTION ENDONUCLEASE PATTERNS OF HERPES-SIMPLEX VIRUS-DNA - SUBTYPING OF HSV-1 AND HSV-2 STRAINS FROM GENITAL AND NONGENITAL LESIONS

被引：1

作者：

HAMELIN, C

PRAMATAROVA, A

PORTNOY, J

GERSON, M

机构：

[1] SIR MORTIMER B DAVIS JEWISH HOSP,DEPT MICROBIOL,MONTREAL H3T 1E2,QUEBEC,CANADA

[2] REDDY MEM HOSP,DEPT MICROBIOL,MONTREAL,QUEBEC,CANADA

来源：

COMPARATIVE IMMUNOLOGY MICROBIOLOGY AND INFECTIOUS DISEASES | 1991年 / 14卷 / 01期

关键词：

AGAROSE GEL ELECTROPHORESIS; DNA; GENOTYPING; HERPESVIRUS; RESTRICTION ENDONUCLEASES;

D O I：

10.1016/0147-9571(91)90039-G

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Herpes simplex type 1 (HSV-1) and type 2 (HSV-2) isolates from genital and nongenital infections were submitted to restriction endonuclease analysis for possible genomic changes in relation with the adaptation of the virus to a new site on the body. HSV-1 and HSV-2 strains were successfully divided into two subgroups using the Hinc II restriction enzyme. No correlation was found, however, between the proposed genomic subtypes H1A, H1B, H2A and H2B, and the genital or nongenital origin of the HSV strains.

引用

页码：39 / 45

页数：7

共 17 条

[1]

DOCHERTY JJ, 1985, J MED VIROL, V16, P286

[2] RELIABLE IDENTIFICATION OF HERPES-SIMPLEX VIRUSES BY DNA RESTRICTION ENDONUCLEASE ANALYSIS WITH ECORI [J].