ISOLATION OF PROCATHEPSIN-D FROM MATURE CATHEPSIN-D BY PEPSTATIN AFFINITY-CHROMATOGRAPHY - AUTOCATALYTIC PROTEOLYSIS OF THE ZYMOGEN FORM OF THE ENZYME

被引:57
作者
CONNER, GE
机构
关键词
D O I
10.1042/bj2630601
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
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页码:601 / 604
页数:4
相关论文
共 12 条
[1]  
CONNER GE, 1987, LYSOSOMES THEIR ROLE, P151
[2]   CONVERSION OF PEPSINOGEN INTO PEPSIN IS NOT A ONE-STEP PROCESS [J].
DYKES, CW ;
KAY, J .
BIOCHEMICAL JOURNAL, 1976, 153 (01) :141-144
[3]   CARBOXYL-TERMINAL PROTEOLYTIC PROCESSING DURING BIOSYNTHESIS OF THE LYSOSOMAL-ENZYMES BETA-GLUCURONIDASE AND CATHEPSIN-D [J].
ERICKSON, AH ;
BLOBEL, G .
BIOCHEMISTRY, 1983, 22 (22) :5201-5205
[4]  
ERICKSON AH, 1981, J BIOL CHEM, V256, P1224
[5]   CLONING AND SEQUENCE-ANALYSIS OF CDNA FOR HUMAN CATHEPSIN-D [J].
FAUST, PL ;
KORNFELD, S ;
CHIRGWIN, JM .
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1985, 82 (15) :4910-4914
[6]   LYSOSOMAL-ENZYME PRECURSORS IN HUMAN-FIBROBLASTS - ACTIVATION OF CATHEPSIN-D PRECURSOR INVITRO AND ACTIVITY OF BETA-HEXOSAMINIDASE-A PRECURSOR TOWARDS GANGLIOSIDE GM2 [J].
HASILIK, A ;
VONFIGURA, K ;
CONZELMANN, E ;
NEHRKORN, H ;
SANDHOFF, K .
EUROPEAN JOURNAL OF BIOCHEMISTRY, 1982, 125 (02) :317-321
[7]  
HUANG JS, 1979, J BIOL CHEM, V254, P1405
[8]   INTERACTION OF HUMAN CATHEPSIN-D WITH INHIBITOR PEPSTATIN [J].
KNIGHT, CG ;
BARRETT, AJ .
BIOCHEMICAL JOURNAL, 1976, 155 (01) :117-125
[9]  
MARCINISZYN J, 1976, J BIOL CHEM, V251, P7095
[10]  
SAPOLSKY AI, 1972, J BIOL CHEM, V247, P2069