ROUTINE QUANTITATIVE-ANALYSIS OF BRAIN AND CEREBROSPINAL-FLUID SPACES WITH MR IMAGING

被引：207

作者：

KIKINIS, R

SHENTON, ME

GERIG, G

MARTIN, J

ANDERSON, M

METCALF, D

GUTTMANN, CRG

MCCARLEY, RW

LORENSEN, W

CLINE, H

JOLESZ, FA

机构：

[1] Department of Radiology, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, 02115

[2] Department of Psychiatry, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts, 02115

[3] Communication Technology Laboratory, Image Science Division, Eth. Zurich

[4] Ge Corporate Research and Development Center., New York, Schenectady

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1992年 / 2卷 / 06期

关键词：

BRAIN; MR; CEREBROSPINAL FLUID; COMPARATIVE STUDIES; IMAGE DISPLAY; IMAGE PROCESSING; 3-DIMENSIONAL IMAGING; VOLUME MEASUREMENT;

D O I：

10.1002/jmri.1880020603

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A computerized system for processing spin-echo magnetic resonance (MR) imaging data was implemented to estimate whole brain (gray and white matter) and cerebrospinal fluid volumes and to display three-dimensional surface reconstructions of specified tissue classes. The techniques were evaluated by assessing the radiometric variability of MR volume data and by comparing automated and manual procedures for measuring tissue volumes. Results showed (a) the homogeneity of the MR data and (b) that automated techniques were consistently superior to manual techniques. Both techniques, however, were affected by the complexity of the structure, with simpler structures (eg, the intracranial cavity) showing less variability and better spatial correlation of segmentation results between raters. Moreover, the automated techniques were completed for whole brain in a fraction of the time required to complcte the equivalent segmentation manually. Additional evaluations included interrater reliability and an evaluation that included longitudinal measurement, in which one subject was imaged sequentially 24 times, with reliability computed from data collected by three raters over 1 year. Results showed good reliability for the automated segmentation procedures.

引用

页码：619 / 629

页数：11

共 27 条

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