GENERAL-METHOD FOR THE SYNTHESIS OF 5-ARYLPYRROLE-2-CARBOXYLIC ACIDS

被引：35
作者：
EZQUERRA, J
PEDREGAL, C
RUBIO, A
VALENCIANO, J
NAVIO, JLG
ALVAREZBUILLA, J
VAQUERO, JJ
机构：
[1] UNIV ALCALA DE HENARES,DEPT QUIM ORGAN,E-28871 ALCALA DE HENARES,SPAIN
[2] CTR INVEST LILLY SA,E-28130 VALDEOLMOS,SPAIN
来源：
TETRAHEDRON LETTERS | 1993年 / 34卷 / 39期
关键词：
PYROGLUTAMATE; ETHYL; 5-ARYLPYRROLE-2-CARBOXYLATE; DDQ; OXIDATIVE AROMATIZATION;
D O I：
10.1016/S0040-4039(00)73741-5
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
5-Arylpyrrole-2-carboxylic acids are prepared by DDQ oxidative aromatization of the corresponding ethyl 2-aryl-DELTA1-pyrroline-5-carboxylate followed by basic hydrolysis.
引用
收藏
页码：6317 / 6320
页数：4
相关论文
共 17 条
  • [1] AZABUTADIENE DERIVATIVES IN THE SYNTHESIS OF 5-MEMBERED HETEROCYCLES - UNEQUIVOCAL SYNTHESIS OF 1H-PYRROLE-2-CARBOXYLATES
    BARLUENGA, J
    RUBIO, V
    GOTOR, V
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1982, 47 (09) : 1696 - 1698
  • [2] BOUKOUPOBA JP, 1979, TETRAHEDRON LETT, V19, P1717
  • [3] REGIOSELECTIVE NUCLEOPHILIC-ATTACK ON N-BOC-PYROGLUTAMATE ETHYL-ESTER
    EZQUERRA, J
    DEMENDOZA, J
    PEDREGAL, C
    RAMIREZ, C
    [J]. TETRAHEDRON LETTERS, 1992, 33 (38) : 5589 - 5590
  • [4] A MILD 2-STEP METHOD FOR THE HYDROLYSIS METHANOLYSIS OF SECONDARY AMIDES AND LACTAMS
    FLYNN, DL
    ZELLE, RE
    GRIECO, PA
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1983, 48 (14) : 2424 - 2426
  • [5] AN EFFICIENT, REGIOCONTROLLED SYNTHESIS OF 5-ARYL-2-CARBETHOXYPYRROLES FROM 3-ARYL-3-CHLOROPROPENIMINIUM SALTS
    GUPTON, JT
    KROLIKOWSKI, DA
    YU, RH
    VU, P
    SIKORSKI, JA
    DAHL, ML
    JONES, CR
    [J]. JOURNAL OF ORGANIC CHEMISTRY, 1992, 57 (20) : 5480 - 5483
  • [6] STEREOSELECTIVE ACETOXYLATION OF CHIRAL PHENYLACETIC ESTERS
    GUY, A
    LEMOR, A
    IMBERT, D
    LEMAIRE, M
    [J]. TETRAHEDRON LETTERS, 1989, 30 (03) : 327 - 330
  • [7] HEMETSBERGER H, 1977, J CHEM RES S, P247
  • [8] MAKATA S, 1982, SYNTHESIS-STUTTGART, V2, P157
  • [9] MOLINA MT, 1993, TETRAHEDRON, V49, P3808
  • [10] SYNTHESIS OF PYRROLE DERIVATIVES FROM 5,6-DIHYDRO-4H-1,2-OXAZINES VIA REDUCTIVE DEOXYGENATION BY USE OF FE3(CO)12
    NAKANISHI, S
    OTSUJI, Y
    ITOH, K
    HAYASHI, N
    [J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1990, 63 (12) : 3595 - 3600
12