METABOLIC-ACTIVATION OF 2-AMINOFLUORENE BY ISOLATED RAT-LIVER CELLS THROUGH DIFFERENT PATHWAYS LEADING TO HEPATOCELLULAR DNA-REPAIR AND BACTERIAL MUTAGENESIS

被引：21
作者：
BROUNS, RME
VANDOORN, R
BOS, RP
MULLENERS, LJS
HENDERSON, PT
机构：
来源：
TOXICOLOGY | 1981年 / 19卷 / 01期
关键词：
D O I：
10.1016/0300-483X(81)90066-4
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
引用
收藏
页码：67 / 75
页数：9
相关论文
共 26 条
[1]   METHODS FOR DETECTING CARCINOGENS AND MUTAGENS WITH SALMONELLA-MAMMALIAN-MICROSOME MUTAGENICITY TEST [J].
AMES, BN ;
MCCANN, J ;
YAMASAKI, E .
MUTATION RESEARCH, 1975, 31 (06) :347-363
[2]  
ANDERSSON B, 1978, DRUG METAB DISPOS, V6, P611
[3]   STUDIES ON MUTAGENICITY OF N-HYDROXY-2-ACETYLAMINOFLUORENE IN AMES-SALMONELLA MUTAGENESIS TEST SYSTEM [J].
ANDREWS, LS ;
HINSON, JA ;
GILLETTE, JR .
BIOCHEMICAL PHARMACOLOGY, 1978, 27 (20) :2399-2408
[4]   ELECTROPHILIC N-ACETOXYAMINOARENES DERIVED FROM CARCINOGENIC N-HYDROXY-N-ACETYLAMINOARENES BY ENZYMATIC DEACETYLATION AND TRANSACETYLATION IN LIVER [J].
BARTSCH, H ;
DWORKIN, M ;
MILLER, JA ;
MILLER, EC .
BIOCHIMICA ET BIOPHYSICA ACTA, 1972, 286 (02) :272-298
[5]   FORMATION OF ELECTROPHILIC N-ACETOXYARYLAMINES IN CYTOSOLS FROM RAT MAMMARY-GLAND AND OTHER TISSUES BY TRANSACETYLATION FROM CARCINOGEN N-HYDROXY-4-ACETYLAMINOBIPHENYL [J].
BARTSCH, H ;
DWORKIN, C ;
MILLER, EC ;
MILLER, JA .
BIOCHIMICA ET BIOPHYSICA ACTA, 1973, 304 (01) :42-55
[6]   HIGH-YIELD PREPARATION OF ISOLATED RAT LIVER PARENCHYMAL CELLS - A BIOCHEMICAL AND FINE STRUCTURAL STUDY [J].
BERRY, MN ;
FRIEND, DS .
JOURNAL OF CELL BIOLOGY, 1969, 43 (03) :506-+
[7]   MUTAGENIC EFFECTS OF BENZO[ALPHA]PYRENE AFTER METABOLIC ACTIVATION BY HEPATIC 9000-G SUPERNATANTS OR INTACT HEPATOCYTES [J].
BROUNS, RE ;
BOS, RP ;
VANGEMERT, PJL ;
YIHVANDEHURK, EWM ;
HENDERSON, PT .
MUTATION RESEARCH, 1979, 62 (01) :19-26
[8]   MEASUREMENT OF DNA-EXCISION REPAIR IN SUSPENSIONS OF FRESHLY ISOLATED RAT HEPATOCYTES AFTER EXPOSURE TO SOME CARCINOGENIC COMPOUNDS - ITS POSSIBLE USE IN CARCINOGENICITY SCREENING [J].
BROUNS, RE ;
POOT, M ;
VRIND, RD ;
HOEKKON, TV ;
HENDERSON, PT ;
KUYPER, CMA .
MUTATION RESEARCH, 1979, 64 (06) :425-432
[9]   METABOLIC-ACTIVATION OF 2-ACETYLAMINOFLUORENE BY ISOLATED RAT-LIVER CELLS - INVOLVEMENT OF DIFFERENT METABOLITES CAUSING DNA-REPAIR AND BACTERIAL MUTAGENESIS [J].
BROUNS, RME ;
BOS, RP ;
DOORN, RV ;
HENDERSON, PT .
ARCHIVES OF TOXICOLOGY, 1980, 45 (01) :53-59
[10]  
CRAMER JW, 1960, J BIOL CHEM, V235, P885
123