IRREVERSIBLE ENZYME INHIBITORS .172. PROTEOLYTIC ENZYMES .16. COVALENT BONDING OF SULFONYL FLUORIDE GROUP TO SERINE OUTSIDE ACTIVE SITE OF ALPHA-CHYMOTRYPSIN BY EXO-TYPE ACTIVE-SITE DIRECTED IRREVERSIBLE INHIBITORS

被引：12

作者：

CARDINAU.R

BAKER, BR

机构：

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1970年 / 13卷 / 03期

关键词：

D O I：

10.1021/jm00297a030

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

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收藏

页码：467 / &

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[2] IRREVERSIBLE ENZYME INHIBITORS .165. PROTEOLYTIC ENZYMES .15. INHIBITION OF GUINEA PIG COMPLEMENT BY DERIVATIVES OF M-PHENOXYPROPOXYBENZAMIDINE
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[3] TISSUE-SPECIFIC IRREVERSIBLE INHIBITORS OF DIHYDROFOLIC REDUCTASE
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[4] IRREVERSIBLE ENZYME INHIBITORS .125. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF XANTHINE OXIDASE DERIVED FROM ARYLPURINES AND PYRAZOLO[3,4-D]PYRIMIDINES BEARING A TERMINAL SULFONYL FLUORIDE
BAKER, BR
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[5] BAKER BR, 1970, J MED CHEM, V13, P461, DOI 10.1021/jm00297a029
[6] IRREVERSIBLE ENZYME INHIBITORS . 144 . PROTEOLYTIC ENZYMES .7. ADDITIONAL ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF TRYPSIN DERIVED FROM M- AND P-(PHENOXYALKOXY)BENZAMIDINES WITH A TERMINAL SULFONYL FLUORIDE
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (01) : 112 - &
[7] IRREVERSIBLE ENZYME INHIBITORS .115. PROTEOLYTIC ENZYMES .5. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF TRYPSIN DERIVED FROM P-(PHENOXYALKOXY)BENZAMIDINES WITH A TERMINAL SULFONYL FLUORIDE
BAKER, BR
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1968, 11 (02) : 245 - &
[8] IRREVERSIBLE ENZYME INHIBITORS .150. PROTEOLYTIC ENZYMES .9. (3,4-DICHLOROPHENOXYACETAMIDO)PYRIDINES BRIDGED BY A QUATERNARY SALT TO A TERMINAL SULFONYL FLUORIDE . POTENT IRREVERSIBLE INHIBITORS OF ALPHA-CHYMOTRYPSIN
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (02) : 221 - &
[9] IRREVERSIBLE ENZYME INHIBITORS .145. PROTEOLYTIC ENZYMES .8. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF ALPHA-CHYMOTRYPSIN DERIVED FROM ALPHA-(2-CARBOXY-4-CHLOROPHENOXY)ACETAMIDE BEARING A TERMINAL SULFONYL FLUORIDE
BAKER, BR
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[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1969, 12 (01) : 118 - &
[10] IRREVERSIBLE ENZYME INHIBITORS .113. PROTEOLYTIC ENZYMES .3. ACTIVE-SITE-DIRECTED IRREVERSIBLE INHIBITORS OF ALPHA-CHYMOTRYPSIN DERIVED FROM PHENOXYACETAMIDES WITH AN N-FLUOROSULFONYLPHENYL SUBSTITUENT
BAKER, BR
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