Technology is a natural part of education for all students across a variety of subjects, including mathematics, as educators work to prepare students for tomorrow's work force and align their curriculum and teaching with national standards such those developed by the National Council of Teachers of Mathematics (NCTM, 2000). This article reviews the literature on mathematics, assistive technology (AT), and educating students with high-incidence disabilities in grades K-12 from 1996 through 2007. The results of the literature review revealed three main areas of AT in mathematics for students with disabilities: anchored instruction, computer-assisted instruction, and calculators. The review focuses on what has been done and suggests that we do know some things in terms of effective AT and mathematics education (i.e., anchored instruction). It then discusses where the field needs to go to improve its knowledge base (i.e., researching AT currently used in the teaching and learning of mathematics, and researching recent innovations in mathematics technology).