ALLOCORTICAL INVOLVEMENT IN HUNTINGTONS-DISEASE

被引:62
作者
BRAAK, H [1 ]
BRAAK, E [1 ]
机构
[1] UNIV FRANKFURT,DEPT ANAT,W-6000 FRANKFURT,GERMANY
关键词
HUNTINGTONS DISEASE; ALLOCORTEX; ENTORHINAL REGION; SUBICULUM; NEURONAL LOSS; LIPOFUSCIN;
D O I
10.1111/j.1365-2990.1992.tb00824.x
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Seven brains of individuals who had suffered from Huntington's disease and seven control brains were examined. Preparations stained for Nissl material and lipofuscin pigment revealed a characteristic layer-specific loss of nerve cells in two allocortical areas, the entorhinal region and the subiculum. The most severe changes occurred in the entorhinal layer Pri-gamma while layer Pre-alpha, layer Pre-gamma and the subiculum showed less severe alterations.
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页码:539 / 547
页数:9
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