HIGHLY REGIOSELECTIVE, (E)-STEREOSELECTIVE AND DIASTEREOSELECTIVE SN2' ADDITION OF ORGANOCUPRATES TO CHIRAL ALLYLIC CYCLIC CARBONATES

被引：25

作者：

KANG, SK

LEE, DH

SIM, HS

LIM, JS

机构：

[1] Department of Chemistry, Sung Kyun Kwan University, Suwon, 440-746, Natural Science Campus

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 01期

关键词：

D O I：

10.1016/S0040-4039(00)60065-5

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Reaction of the cyclic carbonates of acyclic vinyl diols with RCu(CN)Li.BF3, RCu(CN)MgBr-BF3, or RMgBr.CuI (cat) in THF at -78-degrees-C proceeded in S(N)2' fashion and resulted in the formation of alkylated (E)-allylic alcohols with remarkably high diastereoselectivity. This reaction represents an efficient 1, 3-chirality transfer method.

引用

页码：91 / 94

页数：4

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