STAGE-SPECIFIC EXPRESSION OF A DEVELOPMENTALLY REGULATED GENE IN DIROFILARIA-IMMITIS

被引：4
|
作者：
SUN, S [1 ]
MATSUURA, T [1 ]
SUGANE, K [1 ]
机构：
[1] SHINSHU UNIV, FAC MED, DEPT PARASITOL, ASAHI 3-1-1, MATSUMOTO, NAGANO 390, JAPAN
来源：
JOURNAL OF HELMINTHOLOGY | 1992年 / 66卷 / 01期
关键词：
DIROFILARIA-IMMITIS; CDNA CLONE; LARVA-SPECIFIC ANTIGEN; DEVELOPMENTALLY REGULATED GENE;
D O I：
10.1017/S0022149X00012578
中图分类号：
R38 [医学寄生虫学]; Q [生物科学];
学科分类号：
07 ; 0710 ; 09 ; 100103 ;
摘要：
A previously reported cDNA clone encoding 34 kDa antigenic polypeptide of Dirofilaria immitis (lambda-cD34) was studied to elucidate the mechanism of stage-specific gene expression. The 34 kDa polypeptide was a larva-specific antigen and the mRNA was detectable in microfilariae but not in adult worms and eggs. The lambda-cD34 gene was not sex linked and was contained in the genome of D. immitis at each stage. The stage-specific expression of the developmentally regulated gene in D. immitis may bc controlled primarily at the mRNA level.
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收藏
页码：62 / 67
页数：6
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