ULTRASTRUCTURAL-STUDY OF THE CHOROID-PLEXUS OF SPONTANEOUSLY HYPERTENSIVE RATS

被引：9

作者：

RUCHOUX, MM

ROSATI, C

GELOT, A

LHUINTRE, Y

GARAY, R

机构：

[1] CHU Bretonneau Tours INSERM U 7, Hopital Necker, Paris

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1992年 / 5卷 / 11期

关键词：

CHOROID PLEXUS; SPONTANEOUSLY HYPERTENSIVE RAT; STROKE-PRONE SPONTANEOUSLY HYPERTENSIVE RAT; ULTRASTRUCTURE; ION TRANSPORT;

D O I：

10.1093/ajh/5.11.851

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

We previously gave an account of an increased ion transport activity in choroid plexus from spontaneously hypertensive rats.1 We have since examined this organ in scanning and transmission electronic microscopy. In the choroid plexus from young spontaneously hypertensive rats, the epithelial cells showed the following: a partial loss of the brush border and infoldings of basolateral membranes, an increased number of Golgi apparatus, vesicles, and mitochondriae, and an activated nucleus. In adult hypertensive rats, the mithochondriae had increased in number and tended to fill the cytoplasma while the nuclei had returned to a resting level. These ultrastructural changes furthermore suggest an increased secretory activity in the choroid plexus in spontaneously hypertensive rats.

引用

页码：851 / 856

页数：6

共 17 条

[1]

Rosati C., Ruchoux M.M., Et al., Cellular aspects of [Na+, K+, Cl“]-cotransport system in primary hypertension studies in red cells and in the choroid plexus of spontaneously rats (SHR), Cellular Aspects of Hypertension, pp. 257-261, (1992)

[2]

Duhm J., Gobel B.O., Beck F.X., Sodium and potassium ion transport accelerations in erythrocytes of CDOC, DOC- salt, one-clip, two kidney and spontaneously hypertensive rats: Role of hypokalemia and cell volume, Hypertension, 5, pp. 642-652, (1983)

[3]

Feig U.P., Michell P.P., Boylan J.W., Erythrocyte membrane transport in hypertensive humans and rats: Effect of sodium depletion and excess, Hypertension, 7, pp. 423-429, (1985)

[4]

Saitta M.N., Haennaert P.A., Rosati C., Et al., A kinetic analysis of inward Na+, K+ cotransport in erythrocytes from spontaneously hypertensive rats, J Hypertens, 5, pp. 285-286, (1987)

[5]

O'donnel M.E., Owen N.E., Reduced Na-K-Cl-cotransport in vascular smooth muscle cell from spontaneously hypertensive rats, Am J Physiol, 255, pp. C169-C180, (1988)

[6]

Mackinley M.J., McAllen R.M., Mendelsohn F., Et al., Circumventricular organs: Neuroendocrine interfaces between the brain and the hemal milieu, Frontiers in Neuroendocrinology, pp. 91-127, (1990)

[7]

Cserr H.F., Physiology of the choroid plexus, Physiol Rev, 51, pp. 273-311, (1974)

[8]

Rapoport S.I., Blood Brain Barrier Physiology and Medicine, (1976)

[9]

McComb J.G., Recent research into the nature of cerebrospinal fluid formation and absorption, J Neurosurg, 59, pp. 369-383, (1983)

[10]

Wright E.M., Transport processes in the formation of cerebrospinal fluid, Rev Physiol Biochem Pharmacol, 83, pp. 3-34, (1978)

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