Small-cell lung cancer. Diagnostic and therapeutic recommendations of Polish Lung Cancer Group

被引:0
作者
Krzakowski, Maciej [1 ]
Orlowski, Tadeusz [2 ]
Roszkowski, Kazimierz [2 ]
Reinfuss, Marian [3 ]
Olszewski, Wlodzimierz [1 ]
Ramlau, Rodryg [4 ]
Kowalski, Dariusz [1 ]
Konopa, Krzysztof [5 ]
Jassem, Jacek [5 ]
Jankowska, Renata [6 ]
Kozielski, Jerzy [7 ]
Wojtukiewicz, Marek [8 ]
Drosik, Kazimierz [9 ]
Koralewski, Piotr [10 ]
机构
[1] Inst Warszawie, Ctr Onkol, Warsaw, Poland
[2] Inst Chorob Pluc & Gruzlicy Warszawie, Warsaw, Poland
[3] Inst Krakowie, Ctr Onkol, Krakow, Poland
[4] Wielkopolskie Ctr Chorob Pluc & Gruzlicy Poznaniu, Poznan, Poland
[5] Akad Medyczna Gdansku, Gdansk, Poland
[6] Akad Med Wroclawiu, Wroclaw, Poland
[7] Akad Med Zabrzu, Zabrze, Poland
[8] Akad Med Bialymstoku, Bialystok, Poland
[9] Wojewodzki Osrodek Onkol Opolu, Opole, Poland
[10] Wojewodzki Szpital Specjalisty Krakowie, Krakow, Poland
来源
ONCOLOGY IN CLINICAL PRACTICE | 2007年 / 3卷 / 01期
关键词
small-cell lung cancer; diagnosis; staging; recommendations; chemotherapy; radiotherapy; surgical treatment;
D O I
暂无
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Small-cell lung cancer is characterised by an aggressive course with high tendency for early dissemination. At presentation, patients are usually symptomatic and with hilar or mediastinal mass at radiography. Staging should be focused on identifying any evidence of distant spread. Chemotherapy including cisplatin and etoposide is a cornerstone of treatment for all patients. Limited-stage disease should be managed by chemotherapy combined with concurrent chest irradiation. All patients who achieve complete response should be considered for elective cranial irradiation. Surgical treatment may be used in highly selected patients with TNM stage I disease, and surgery should always be combined with chemotherapy. Extensive-stage disease should be managed by multi-agent chemotherapy alone. Long-term survivors should undergo careful monitoring for development of a second primary tumour.
引用
收藏
页码:1 / 7
页数:7
相关论文
共 35 条
[21]   Early versus late chest radiotherapy for limited stage small cell lung cancer [J].
Pijls-Johannesma, MCG ;
De Ruysscher, D ;
Lambin, P ;
Rutten, I ;
Vansteenkiste, JF .
COCHRANE DATABASE OF SYSTEMATIC REVIEWS, 2005, (01)
[22]  
Pujol JL, 2000, BRIT J CANCER, V83, P8
[23]   Small cell lung cancer [J].
Rosti, G ;
Bevilacqua, G ;
Bidoli, P ;
Portalone, L ;
Santo, A ;
Genestreti, G .
ANNALS OF ONCOLOGY, 2006, 17 :5-10
[24]   Chemotherapy as treatment of primary and recurrent small cell lung cancer [J].
Schuette, W .
LUNG CANCER, 2001, 33 :S99-S107
[25]  
Simon G, 2001, Chest Surg Clin N Am, V11, P165
[26]   Progress in the therapy of small cell lung cancer [J].
Simon, M ;
Argiris, A ;
Murren, JR .
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY, 2004, 49 (02) :119-133
[27]   Drug therapy: Multidisciplinary management of lung cancer [J].
Spira, A ;
Ettinger, DS .
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 350 (04) :379-392
[28]   Early compared with late radiotherapy in combined modality treatment for limited disease small-cell lung cancer: A London Lung Cancer Group multicenter randomized clinical trial and meta-analysis [J].
Spiro, Stephen G. ;
James, Lindsay E. ;
Rudd, Robin M. ;
Trask, Colin W. ;
Tobias, Jeffrey S. ;
Snee, Michael ;
Gilligan, David ;
Murray, Philip A. ;
Carmen Ruiz de Elvira, Mary ;
O'Donnell, Katy M. ;
Gower, Nicole H. ;
Harper, Peter G. ;
Hackshaw, Allan K. .
JOURNAL OF CLINICAL ONCOLOGY, 2006, 24 (24) :3823-3830
[29]  
Syphard J. E., J THORAC CARDIOVASC, V205, P64
[30]  
Travis WD, 1999, HISTOLOGICAL TYPING