SIDE-EFFECTS OF MIXED AGONIST-ANTAGONIST ANALGESICS USED IN SEQUENTIAL ANESTHESIA

被引：1

作者：

DEVAUX, C ^{[1
]}

SCHOEPFFLER, P ^{[1
]}

GAUTHIERLAFAYE, JP ^{[1
]}

机构：

[1] CTR HOSP UNIV STRASBOURG,F-67000 STRASBOURG,FRANCE

来源：

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY | 1979年 / 7卷

关键词：

D O I：

10.1111/j.1365-2125.1979.tb04708.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

1 Mixed agonist‐antagonist analgesics have analgesic action but also possess a range of side‐effects. 2 Narcotic antagonists do not reverse the non‐specific effects of opiates. 3 Under certain circumstances the effects of agonists and mixed agonist‐antagonists can be additive. 4 Chronic dosage of mixed agonist‐antagonists leads to a lower level of dependence than that observed with the standard narcotics. 5 Mixed agonist‐antagonists may not antagonize the respiratory effects of narcotics and may result in potentiation of such depression. 1979 The British Pharmacological Society

引用

页码：S323 / S326

页数：4

共 9 条

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