MECHANISM OF HETEROCYCLIC RING EXPANSIONS .3. REACTION OF PYRROLES WITH DICHLOROCARBENE

被引：31

作者：

JONES, RL

REES, CW

机构：

[1] King's College

来源：

JOURNAL OF THE CHEMICAL SOCIETY C-ORGANIC | 1969年 / 17期

关键词：

D O I：

10.1039/j39690002249

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

2,5-Dimethyl-, 2,3,4,5-tetramethyl-, and 3,4-dimethyl-2,5-diphenyl-1H- pyrrole react with dichlorocarbene in basic solution to give 2-dichloromethyl-2H-pyrrole and 3-chloropyridines in low yield. However, in neutral aprotic solution high yields of 3-chloropyridines are formed in a synthetically useful reaction; 2H-pyrroles are not formed. These results support earlier mechanistic proposals.

引用

页码：2249 / &

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