EPIDERMAL GROWTH-FACTOR - INDUCED IMPLANTATION AND DECIDUALIZATION IN THE RAT

被引：24
|
作者：
TAMADA, H
KAI, Y
MORI, J
机构：
[1] Department of Animal Reproduction, College of Agriculture, University of Osaka Prefecture, Sakai, Osaka
来源：
PROSTAGLANDINS | 1994年 / 47卷 / 06期
关键词：
EGF; IMPLANTATION; DECIDUALIZATION; INDOMETHACIN; RAT;
D O I：
10.1016/0090-6980(94)90046-9
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Effects of epidermal growth factor (EGF) on blastocyst implantation and experimentally-induced decidualization were examined in the rat. Intraluminal injection of EGF into each uterine horn induced implantation in the ovariectomized progesterone-treated delayed implanting rat in a dose-dependent manner. This induction was inhibited by indomethacin, an inhibitor of prostaglandin synthesis. Intraluminal injection of EGF on day 5 of pseudopregnancy elicited a greater decidual response when compared to the vehicle-injected contralateral uterine horn. These results suggest that EGF may play important roles in the process of implantation and decidualization in the rat.
引用
收藏
页码：467 / 475
页数：9
相关论文
共 50 条
  • [1] Improvement of rat embryo implantation by epidermal growth factor
    Hanada, K
    Hattori, M
    Fujihara, N
    JOURNAL OF APPLIED ANIMAL RESEARCH, 1997, 12 (01) : 71 - 80
  • [2] RAT OOCYTES INDUCED TO MATURE BY EPIDERMAL GROWTH-FACTOR ARE SUCCESSFULLY FERTILIZED
    BENYOSEF, D
    GALIANI, D
    DEKEL, N
    SHALGI, R
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 1992, 88 (1-3) : 135 - 141
  • [3] FIBROBLAST GROWTH-FACTOR INHIBITS EPIDERMAL GROWTH FACTOR-INDUCED RESPONSES IN RAT ASTROCYTES
    HUFF, KR
    SCHREIER, W
    GLIA, 1990, 3 (03) : 193 - 204
  • [4] EPIDERMAL GROWTH-FACTOR REACTIVITY IN RAT MILK
    RAABERG, L
    NEXO, E
    TOLLUND, L
    POULSEN, SS
    CHRISTENSEN, SB
    CHRISTENSEN, MS
    REGULATORY PEPTIDES, 1990, 30 (02) : 149 - 157
  • [5] EFFECTS OF EPIDERMAL GROWTH-FACTOR ON NEONATAL GROWTH OF RAT INTESTINES
    ODAKA, K
    HIRAMATSU, Y
    EGUCHI, K
    KUDO, T
    ACTA MEDICA OKAYAMA, 1994, 48 (01) : 47 - 50
  • [6] EPIDERMAL GROWTH-FACTOR STIMULATES THYROTROPIN SECRETION IN THE RAT
    ALTSCHULER, LR
    PARISI, MN
    CAGEAO, LF
    CHIOCCHIO, SR
    FERNANDEZPOL, JA
    ZANINOVICH, AA
    NEUROENDOCRINOLOGY, 1993, 57 (01) : 23 - 27
  • [7] IMMUNOHISTOCHEMICAL LOCALIZATION OF EPIDERMAL GROWTH-FACTOR RECEPTOR DURING IMPLANTATION IN THE RABBIT
    HOFMANN, GE
    ANDERSON, TL
    AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY, 1990, 162 (03) : 837 - 841
  • [8] EPIDERMAL GROWTH-FACTOR EXPRESSION IN JUNCTIONAL EPITHELIUM OF RAT GINGIVA
    TAJIMA, Y
    YOKOSE, S
    KASHIMATA, M
    HIRAMATSU, M
    MINAMI, N
    UTSUMI, N
    JOURNAL OF PERIODONTAL RESEARCH, 1992, 27 (04) : 299 - 300
  • [9] IMMUNOHISTOCHEMICAL STUDY OF EPIDERMAL GROWTH-FACTOR AND EPIDERMAL GROWTH-FACTOR RECEPTOR IN BREAST-CARCINOMA
    NOGUCHI, M
    MIZUKAMI, Y
    KINOSHITA, K
    EARASHI, M
    THOMAS, M
    MIYAZAKI, I
    ONCOLOGY REPORTS, 1994, 1 (02) : 381 - 385
  • [10] RENAL UPTAKE AND EXCRETION OF EPIDERMAL GROWTH-FACTOR FROM PLASMA IN THE RAT
    JORGENSEN, PE
    RASMUSSEN, TN
    OLSEN, PS
    RAABERG, L
    POULSEN, SS
    NEXO, E
    REGULATORY PEPTIDES, 1990, 28 (03) : 273 - 280
12345