CONJUGATE-DIRECTION MINIMIZATION - AN IMPROVED METHOD FOR THE REFINEMENT OF MACROMOLECULES

被引：154

作者：

TRONRUD, DE ^{[1
]}

机构：

[1] UNIV OREGON,EUGENE,OR 97403

来源：

ACTA CRYSTALLOGRAPHICA SECTION A | 1992年 / 48卷

关键词：

D O I：

10.1107/S0108767392005415

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A novel method of function minimization that combines the power of the diagonal approximation to the normal matrix with conjugate directions is described. This method approaches closer to the local minimum than the methods that are commonly used in macromolecular refinement. The weaknesses of the current methods are analyzed to explain the advantage of the conjugate-direction method.

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页码：912 / 916

页数：5

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