A QSAR INVESTIGATION OF DIHYDROFOLATE-REDUCTASE INHIBITION BY BAKER TRIAZINES BASED UPON MOLECULAR SHAPE-ANALYSIS

被引：221

作者：

HOPFINGER, AJ

机构：

来源：

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | 1980年 / 102卷 / 24期

关键词：

D O I：

10.1021/ja00544a005

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

引用

收藏

页码：7196 / 7206

页数：11

相关论文

共 27 条

[1] CALCULATION OF STRUCTURES OF HYDROCARBONS CONTAINING DELOCALIZED ELECTRONIC SYSTEMS BY MOLECULAR MECHANICS METHOD
ALLINGER, NL
SPRAGUE, JT
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1973, 95 (12) : 3893 - 3907
[2] [Anonymous], CONFORMATIONAL PROPE
[3] THEORETICAL TREATMENT OF MULTIPLE SITE REACTIVITY IN LARGE MOLECULES
BARTLETT, RJ
WEINSTEIN, H
[J]. CHEMICAL PHYSICS LETTERS, 1975, 30 (03) : 441 - 447
[4] STEREOCHEMISTRY OF DIHYDROFOLATE-REDUCTASE INHIBITOR ANTI-TUMOR AGENTS - MOLECULAR-STRUCTURE OF BAKER ANTIFOL (NSC-139105, TRIAZINATE) AND INSOLUBLE BAKER ANTIFOL (NSC-113423)
CAMERMAN, A
SMITH, HW
CAMERMAN, N
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1978, 83 (01) : 87 - 93
[5] BC(DEF) PARAMETERS .2. EMPIRICAL STRUCTURE-BASED SCHEME FOR THE PREDICTION OF SOME PHYSICAL-PROPERTIES
CRAMER, RD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (06) : 1849 - 1859
[6] BC(DEF) PARAMETERS .1. INTRINSIC DIMENSIONALITY OF INTERMOLECULAR INTERACTIONS IN THE LIQUID-STATE
CRAMER, RD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (06) : 1837 - 1849
[7] DISTANCE GEOMETRY APPROACH TO RATIONALIZING BINDING DATA
CRIPPEN, GM
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1979, 22 (08) : 988 - 997
[8] DIHYDROFOLATE-REDUCTASE INHIBITION BY 2,4-DIAMINOTRIAZINES - STRUCTURE-ACTIVITY STUDY
DIETRICH, SW
SMITH, RN
FUKUNAGA, JY
OLNEY, M
HANSCH, C
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1979, 194 (02) : 600 - 611
[9] USE OF TRIAZINE INHIBITORS IN MAPPING THE ACTIVE-SITE REGION OF LACTOBACILLUS-CASEI DIHYDROFOLATE-REDUCTASE
DIETRICH, SW
SMITH, RN
BRENDLER, S
HANSCH, C
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1979, 194 (02) : 612 - 619
[10] HAM NS, 1974, MOL QUANTUM PHARM, P261