INVIVO AND INVITRO EFFECTS OF ALLOXAN ON COLLAGEN CHARACTERISTICS OF BONE, SKIN AND TENDON OF SWISS MICE

被引：15

作者：

BEHERA, HN ^{[1
]}

PATNAIK, BK ^{[1
]}

机构：

[1] BERHAMPUR UNIV,POST GRAD DEPT ZOOL,BERHAMPUR 760007,ORISSA,INDIA

来源：

GERONTOLOGY | 1979年 / 25卷 / 05期

关键词：

Alloxan diabetes; Collagen; Mouse tissues;

D O I：

10.1159/000212350

中图分类号：

R592 [老年病学]; C [社会科学总论];

学科分类号：

03 ; 0303 ; 100203 ;

摘要：

Alloxan diabetes in Swiss mice induced decreased levels of percent solubility of collagen in bone, skin and tendon both after 4 days (96 h) and 28 days of treatment. In vitro treatment of tissues with alloxan in physiological saline did not influence the cross-linking of collagen. It is suggested that in alloxan diabetes, metabolites formed in the tissues might accelerate aging of collagen. © 1979 S. Karger AG, Basel.

引用

页码：255 / 260

页数：6

共 13 条

[1] CONNECTIVE-TISSUE MACROMOLECULAR CHANGES IN RATS WITH EXPERIMENTALLY INDUCED DIABETES AND HYPERINSULINISM [J].

BERENSON, GS ;

BRICKMAN, F ;

PLAVIDAL, F ;

SRINIVASAN, SR ;

RUIZ, H ;

DALFERES, ER ;

RADHAKRISHNAMURTHY, B .

DIABETES, 1972, 21 (06) :733-+

[2]

BERTOLINI AM, 1969, GERONTOLOGIC METABOL, P176

[3]

BURGESS JA, 1976, HYPOTHALAMUS PITUITA, P496

[4]

Hall D. A., 1976, AGEING CONNECTIVE TI

[5] APPARENT ACCELERATED AGING OF HUMAN COLLAGEN IN DIABETES-MELLITUS [J].

HAMLIN, CR ;

KOHN, RR ;

LUSCHIN, JH .

DIABETES, 1975, 24 (10) :902-904

[6]

JACKSON D. S., 1967, METHODS BIOCHEM ANAL, V15, P25, DOI 10.1002/9780470110331.ch2

[7] ABNORMAL COLLAGEN IN CULTURES OF FIBROBLASTS FROM HUMAN BEINGS WITH DIABETES-MELLITUS [J].

KOHN, RR ;

HENSSE, S .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1977, 76 (03) :765-771

[8] NOTES ON A MODIFICATION OF THE NEUMAN AND LOGAN METHOD FOR THE DETERMINATION OF THE HYDROXYPROLINE [J].

LEACH, AA .

BIOCHEMICAL JOURNAL, 1960, 74 :70-71

[9] A COLORIMETRIC MICRO-METHOD FOR THE DETERMINATION OF GLUCOSE [J].

MENDEL, B ;

KEMP, A ;

MYERS, DK .

BIOCHEMICAL JOURNAL, 1954, 56 (04) :639-646

[10]

NEUMAN RE, 1950, J BIOL CHEM, V186, P549

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