COMPARATIVE IN-VITRO ACTIVITY OF PIPERACILLIN TAZOBACTAM AGAINST RECENT CLINICAL ISOLATES, A DUTCH NATIONAL MULTICENTER STUDY

被引：6
作者：
STOBBERINGH, EE
MACLAREN, DM
SCHMITZ, PIM
DIRKSGO, SIS
DANKERT, J
LIGTVOET, EEJ
LICHTENDAHLBERNARDS, AT
HORREVORTS, AM
THEWESSEN, EAPM
BANFFER, JRJ
WAGENVOORT, JHT
HENDRIKS, WDH
BRIMICOMBE, RW
LIM, BT
VISSER, MR
VANKLINGEREN, B
VANKREGTEN, E
DEJONG, J
SCHREUDER, H
SABBE, LJM
WINTERMANS, RGF
DIEPERSLOOT, RJA
SONDERKAMP, HJA
VANDIJKE, BF
FABIUS, GTJ
DAVIES, BI
HOOGKAMPKORSTANJE, JAA
DEJONG, A
SEVERIN, WPJ
DEGENER, JE
MANSON, WL
VERBRUGH, H
机构：
[1] FREE UNIV AMSTERDAM HOSP,DEPT CLIN MICROBIOL & INFECT CONTROL,AMSTERDAM,NETHERLANDS
[2] DR DANIEL DEN HOED CANC CTR,DEPT TRIALS & STAT,3008 AE ROTTERDAM,NETHERLANDS
来源：
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY | 1994年 / 34卷 / 05期
关键词：
D O I：
10.1093/jac/34.5.777
中图分类号：
R51 [传染病];
学科分类号：
100401 ;
摘要：
In this Dutch national survey piperacillin-tazobactam had a MIC(90) of less than or equal to 8 mg/L for Enterobacteriaceae (Enterobacter cloacae excluded) and Pseudomonas aeruginosa, 64 mg/L for E. cloacae, and 4 mg/L for Acinetobacter spp. The corresponding MIC(90) values for piperacillin alone were less than or equal to 256 mg/L, 256 mg/L, 16 mg/L and 32 mg/L. Only 15 of 93 piperacillin-tazobactam resistant E. cloacae strains were sensitive for ceftazidime, whereas 41 of 93 ceftazidime-resistant E. cloacae were sensitive to piperacillin-tazobactam.
引用
收藏
页码：777 / 783
页数：7
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