BEHAVIORAL TOXICITY OF ANTICHOLINESTERASES IN PRIMATES - CHRONIC PHYSOSTIGMINE AND SOMAN INTERACTIONS

被引：6

作者：

BLICK, DW ^{[1
]}

MILLER, SA ^{[1
]}

BROWN, GC ^{[1
]}

MURPHY, MR ^{[1
]}

机构：

[1] USAF,ARMSTRONG LAB,DIV DIRECTED ENERGY,BROOKS AFB,TX 78235

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1993年 / 45卷 / 03期

关键词：

ORGANOPHOSPHATES; CARBAMATES; ANTICHOLINESTERASES; MACAQUE; TRACKING PERFORMANCE;

D O I：

10.1016/0091-3057(93)90524-W

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

Dose rates for continuous infusion of physostigmine salicylate required to inhibit 30 and 60% of normal serum cholinesterase activity in rhesus monkeys were determined. The effects of continuous physostigmine infusion at these dose rates on the behavioral toxicity of daily repeated low-dose soman were determined not to be deleterious; in fact, they were slightly (and variably) protective.

引用

页码：677 / 683

页数：7

共 35 条

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