NEUROMEDIATOR ANALOGS - SYNTHESIS OF CIS (2R,3S) AND TRANS (2S,3S)-2,3-PIPERIDINE DICARBOXYLIC-ACIDS FROM (2S)-2-PHENYLGLYCINOL

被引：23

作者：

AGAMI, C ^{[1
]}

KADOURIPUCHOT, C ^{[1
]}

LEGUEN, V ^{[1
]}

VAISSERMANN, J ^{[1
]}

机构：

[1] UNIV PARIS 06,CNRS,CHIM MET TRANSIT LAB,F-75005 PARIS,FRANCE

来源：

TETRAHEDRON LETTERS | 1995年 / 36卷 / 10期

关键词：

D O I：

10.1016/0040-4039(95)00088-T

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The cis and trans isomers of 2,3-piperidine dicarboxylic acids were obtained in enantiopure forms from the same chiral inductor: 2-phenylglycinol. This synthesis was mainly based on a delta-lactam formation via Stille's aza-annulation/hydrogenation procedure which includes here an asymmetric induction.

引用

页码：1657 / 1660

页数：4

共 16 条

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