OCULAR TORSION PRODUCED BY UNILATERAL CHEMICAL INACTIVATION OF THE INTERSTITIAL NUCLEUS OF CAJAL IN CHRONICALLY LABYRINTHECTOMIZED CATS

被引：23
作者：
FUKUSHIMA, K
OHASHI, T
FUKUSHIMA, J
KASE, M
机构：
[1] Department of Physiology, Hokkaido University School of Medicine, Sapporo
来源：
NEUROSCIENCE RESEARCH | 1992年 / 13卷 / 04期
关键词：
INTERSTITIAL NUCLEUS OF CAJAL; OCULAR TORSION; VERTICAL EYE MOVEMENT; MUSCIMOL INFUSION; LABYRINTHECTOMY; OCULAR TILT REACTION; NEURAL INTEGRATOR; CAT;
D O I：
10.1016/0168-0102(92)90041-A
中图分类号：
Q189 [神经科学];
学科分类号：
071006 ;
摘要：
Unilateral lesions of the rostral midbrain involving the interstitial nucleus of Cajal (INC have been known to produce ocular torsion in alert animals including humans, which has been assumed to be the result of an impaired otolith-ocular reflex. We examined the effects of chemical deactivation of the INC using a gamma-aminobutyric acid (GABA) agonist (muscimol) in cats that had received bilateral labyrinthectomy, and compared the results with those in normal cats. Ocular torsion with a magnitude similar to that observed in normal cats appeared in chronically labyrinthectomized cats after unilateral muscimol infusion into the INC, indicating that ocular torsion following unilateral INC deactivation can be produced by a mechanism independent of the otolith-ocular reflex.
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收藏
页码：301 / 305
页数：5
相关论文
共 17 条
[1]   OCULAR TORSION IN THE CAT AFTER LESIONS OF THE INTERSTITIAL NUCLEUS OF CAJAL [J].
ANDERSON, JH .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1981, 374 (NOV) :865-871
[2]   GENERATION OF TORSIONAL AND VERTICAL EYE POSITION SIGNALS BY THE INTERSTITIAL NUCLEUS OF CAJAL [J].
CRAWFORD, JD ;
CADERA, W ;
VILIS, T .
SCIENCE, 1991, 252 (5012) :1551-1553
[3]   ACTIVITY OF EYE-MOVEMENT-RELATED NEURONS IN THE REGION OF THE INTERSTITIAL NUCLEUS OF CAJAL DURING SLEEP [J].
FUKUSHIMA, K ;
FUKUSHIMA, J .
NEUROSCIENCE RESEARCH, 1990, 9 (02) :126-139
[4]  
FUKUSHIMA K, 1987, EXP BRAIN RES, V68, P88
[5]  
FUKUSHIMA K, 1990, EXP BRAIN RES, V79, P43
[6]   THE ORIGIN OF HIGH AND REGULAR DISCHARGE RATES OF EYE-MOVEMENT-RELATED NEURONS IN THE REGION OF THE INTERSTITIAL NUCLEUS OF CAJAL [J].
FUKUSHIMA, K ;
FUKUSHIMA, J ;
KASE, M .
NEUROSCIENCE RESEARCH, 1991, 12 (02) :379-387
[7]   THE INTERSTITIAL NUCLEUS OF CAJAL IN THE MIDBRAIN RETICULAR-FORMATION AND VERTICAL EYE-MOVEMENT [J].
FUKUSHIMA, K .
NEUROSCIENCE RESEARCH, 1991, 10 (03) :159-187
[8]  
FUKUSHIMA K, 1990, EXP BRAIN RES, V79, P25
[9]   THE INTERSTITIAL NUCLEUS OF CAJAL AND ITS ROLE IN THE CONTROL OF MOVEMENTS OF HEAD AND EYES [J].
FUKUSHIMA, K .
PROGRESS IN NEUROBIOLOGY, 1987, 29 (02) :107-&
[10]   OCULAR TILT REACTION WITH PERIPHERAL VESTIBULAR LESION [J].
HALMAGYI, GM ;
GRESTY, MA ;
GIBSON, WPR .
ANNALS OF NEUROLOGY, 1979, 6 (01) :80-83
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